Eye Department, Southampton University Hospital, Southampton, Hampshire, United Kingdom.
J Cataract Refract Surg. 2011 Nov;37(11):1993-2000. doi: 10.1016/j.jcrs.2011.05.046.
To compare the visual performance after implantation of the Akreos Adapt Advanced Optics aspheric intraocular lens (IOL) and the Sensar AR40e spherical acrylic IOL.
Eye Department, Southampton University Hospital, United Kingdom.
Randomized masked single-center clinical trial.
Patients with bilateral cataract who were older than 50 years with a biometry-predicted IOL power between 10.0 diopters (D) and 30.0 D were recruited. Outcome measures included corrected distance visual acuity (CDVA) using a high-contrast logMAR chart, contrast sensitivity measured with the Pelli-Robson chart, range of accommodation using the Royal Air Force (RAF) rule, pseudoaccommodation and mesopic and scotopic pupil diameters measured with a power refractor, and patient satisfaction evaluated using a previously validated questionnaire 3 months after second-eye surgery.
The difference in the mean value between the 2 IOLs (40 patients) was 0.015 (95% confidence interval [CI], 0.0009 to 0.070) for CDVA in favor of the spherical IOL, 0.02 (95% CI, -0.0534 to 0.0159) for contrast sensitivity, and 0.05 (95% CI, -1.90 to +2.90) for range of accommodation. Questionnaire results showed no difference in dysphotopsia or patient satisfaction between the 2 IOLs.
Although there were no statistically significant differences in contrast sensitivity, range of accommodation, dysphotopsia, or subjective patient satisfaction or preference between the 2 IOLs, the difference in CDVA was statistically significant, but not clinically important (relative difference 1.5%), in favor of the spherical IOL.
No author has a financial or proprietary interest in any material or method mentioned.
比较 Akreos Adapt 高级光学非球面人工晶状体（IOL）和 Sensar AR40e 球形丙烯酸 IOL 植入后的视觉性能。
英国南安普顿大学医院眼科。
随机、单盲、单中心临床试验。
招募年龄大于 50 岁、生物测量预测 IOL 屈光力在 10.0 屈光度（D）至 30.0 D 之间的双侧白内障患者。主要观察指标包括使用高对比度 logMAR 图表测量的矫正远视力（CDVA）、使用 Pelli-Robson 图表测量的对比敏感度、使用皇家空军（RAF）规则测量的调节范围、使用屈光力折射计测量的假性调节和中间和暗瞳孔直径，以及术后 3 个月使用先前验证的问卷评估患者满意度。
2 种 IOL（40 例患者）的平均值差异为：CDVA 差异为 0.015（95%置信区间[CI]：0.0009 至 0.070），有利于球形 IOL；对比敏感度差异为 0.02（95% CI：-0.0534 至 0.0159）；调节范围差异为 0.05（95% CI：-1.90 至 +2.90）。问卷结果显示，两种 IOL 在畏光或患者满意度方面无差异。
尽管两种 IOL 在对比敏感度、调节范围、畏光、主观患者满意度或偏好方面没有统计学差异，但 CDVA 差异具有统计学意义，但无临床意义（相对差异 1.5%），有利于球形 IOL。
没有作者在任何提到的材料或方法中拥有财务或所有权利益。
