青少年长期用药依从性增强干预措施的系统评价。
A systematic review of adherence-enhancing interventions in adolescents taking long-term medicines.
机构信息
School of Pharmacy, Division of Social Research in Medicines and Health, The University of Nottingham, Nottingham, UK.
出版信息
J Adolesc Health. 2011 Nov;49(5):455-66. doi: 10.1016/j.jadohealth.2011.02.010. Epub 2011 May 28.
PURPOSE
To assess the effectiveness of adherence-enhancing interventions (AEIs) aimed at adolescents (10-19-year-olds).
METHODS
An extensive search of seven bibliographic databases was conducted at the end of 2009 to identify comparative studies evaluating AEIs targeting adolescents. Data describing study characteristics and intervention effects on adherence to medicines or health outcomes were extracted and summarized using qualitative and quantitative methods.
RESULTS
A total of 17 AEIs were identified: 12 studies (70%) were conducted in the United States, 10 (59%) included adolescents with type 1 diabetes mellitus, and 14 (82%) considered the developmental tasks of adolescence. In all, 12 AEIs successfully improved outcome measures. Features of successful interventions included targeting AEIs to a narrow age range, including family in type 1 diabetes mellitus management, and improving access to care. Poor quality and underpowered studies limit the inferences drawn from this review.
CONCLUSIONS
More diverse and robust studies are needed to identify strategies to help adolescents manage medicines.
目的
评估针对青少年（10-19 岁）的增强依从性干预措施（AEIs）的有效性。
方法
2009 年底，我们对 7 个文献数据库进行了广泛搜索，以确定评估针对青少年的 AEIs 的比较研究。使用定性和定量方法提取并总结了描述研究特征和干预对药物或健康结果的依从性的影响的数据。
结果
共确定了 17 项 AEIs：12 项研究（70%）在美国进行，10 项（59%）包括 1 型糖尿病青少年，14 项（82%）考虑到了青少年的发展任务。总的来说，有 12 项 AEIs成功地改善了结果测量。成功干预的特征包括将 AEIs 针对狭窄的年龄范围，包括 1 型糖尿病管理中的家庭，并改善获得医疗的机会。研究质量差和统计效能低限制了从本综述中得出的推论。
结论
需要更多的多样化和强有力的研究来确定帮助青少年管理药物的策略。
Zotero 插件