Department of Otolaryngology-Head & Neck Surgery, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.
J Cyst Fibros. 2012 Mar;11(2):93-9. doi: 10.1016/j.jcf.2011.09.009. Epub 2011 Oct 20.
No guidelines comprise when or to what extent sinus surgery should be done in patients with cystic fibrosis (CF) or how a CT scan of the paranasal sinuses should influence the decision. Symptoms of rhinosinusitis and/or eradication of pathogenic bacteria from the sinuses are reasons for sinus surgery.
In this observational cross sectional study, 55 CF cases had their preoperative CT scans scored according to the Lund Mackay- and the Nair-system. Correlations between the CT scans, symptoms, surgical findings and cultures obtained during sinus surgery were made.
There was no significant correlation between the CT score and detection of pus, pathogenic bacteria or symptoms. Pus and pathogenic bacteria were found in several cases without sinus opacification on the CT scan. Non pathogenic and sterile cultures were also found in sinuses with opacification.
A CT scan is not a valid criterion for sinus surgery in CF patients.
对于囊性纤维化（CF）患者何时以及在何种程度上进行鼻窦手术，以及鼻窦 CT 扫描应如何影响手术决策，目前尚无指南。鼻窦炎的症状和/或鼻窦内致病菌的清除是鼻窦手术的原因。
在这项观察性横断面研究中，对 55 例 CF 患者的术前 CT 扫描进行了 Lund-Mackay 和 Nair 系统评分。对鼻窦手术过程中获得的 CT 扫描、症状、手术发现和培养物之间的相关性进行了分析。
CT 评分与脓液、致病菌或症状的检出之间无显著相关性。在 CT 扫描未见鼻窦混浊的情况下，仍有多处存在脓液和致病菌。在混浊的鼻窦中也发现了非致病性和无菌的培养物。
CT 扫描不能作为 CF 患者鼻窦手术的有效标准。
