Department of Neurosurgery, Hospital General Universitario Gregorio Marañón, C/46 Dr Esquerdo, 28007 Madrid, Spain.
J Clin Neurosci. 2011 Dec;18(12):1662-6. doi: 10.1016/j.jocn.2011.03.008. Epub 2011 Oct 22.
Spinal dural arteriovenous fistulas (SDAVF) are the most frequently occurring vascular malformations of the spinal cord but their optimal treatment remains contentious. We retrospectively analyzed 19 consecutive patients treated between 1996 and 2007. Endovascular embolization was considered the first treatment option for nine patients. Ten patients did not fulfill the endovascular indications and underwent surgery. Four patients required a second treatment with surgery: three following failed embolization and one following surgery. Clinical outcomes were assessed using the Aminoff-Logue disability scale (ALS). The mean follow-up time was 36 months (range=4-103 months). At follow-up, 79% of patients showed stabilization or improvement on the ALS. The overall efficacy of embolization was 55.6%, compared to 100% with surgery (p=0.03). Multidisciplinary treatment with embolization or surgery offers good long-term results. Whenever embolization does not ensure a complete closure of the venous side of the fistula, surgery should be considered as the first treatment because of its lower late recurrence rate.
脊髓硬脊膜动静脉瘘(SDAVF)是脊髓最常见的血管畸形,但它们的最佳治疗方法仍存在争议。我们回顾性分析了 19 例 1996 年至 2007 年间治疗的连续患者。9 例患者被认为是血管内栓塞治疗的首选。10 例患者不符合血管内治疗适应证,接受了手术治疗。4 例患者需要再次手术治疗:3 例栓塞治疗失败,1 例手术治疗后。使用 Aminoff-Logue 残疾量表(ALS)评估临床结果。平均随访时间为 36 个月(范围=4-103 个月)。随访时,79%的患者 ALS 稳定或改善。栓塞的总体疗效为 55.6%,而手术为 100%(p=0.03)。栓塞或手术的多学科治疗可带来良好的长期结果。只要栓塞不能确保瘘静脉侧完全闭合,就应考虑手术作为首选治疗方法,因为其晚期复发率较低。