Endo Toshiki, Endo Hidenori, Sato Kenichi, Matsumoto Yasushi, Tominaga Teiji
Department of Neurosurgery, Tohoku University, Graduate School of Medicine.
Neurol Med Chir (Tokyo). 2016 Aug 15;56(8):457-64. doi: 10.2176/nmc.ra.2015-0327. Epub 2016 Mar 4.
Spinal arteriovenous malformation (AVM) is a broad term that constitutes diverse vascular pathologies. To date, various classification schemes for spinal AVM have been proposed in literature, which helped neurosurgeons understand the pathophysiology of the disease and determine an optimal treatment strategy. To discuss indications and results of surgical and endovascular interventions for spinal AVM, this article refers to the following classification proposed by Anson and Spetzler in 1992: type I, dural arteriovenous fistula (AVF); type II, glomus intramedullary AVM; type III, juvenile malformations; and type IV, perimedullary AVF. In general, complete obliteration of the fistula is a key for better outcome in type I dural and type IV perimedullary AVFs. On the other hand, in type II glomus and type III juvenile malformations, functional preservation, instead of pursuing angiographical cure, is the main goal of the treatment. In such cases, reduction of the shunt flow can alleviate clinical symptoms. Proper management of spinal AVM should start with neurological examination and understanding of angioarchitectures, which provide critical information that guides the indication and modality of intervention. Finally, close collaboration of the microsurgical and endovascular teams are mandatory for successful treatment.
脊髓动静脉畸形(AVM)是一个宽泛的术语,涵盖了多种血管病变。迄今为止,文献中已提出了各种脊髓AVM的分类方案,这有助于神经外科医生了解该疾病的病理生理学并确定最佳治疗策略。为了讨论脊髓AVM的手术和血管内介入治疗的适应证及结果,本文参考了1992年安森(Anson)和斯佩茨勒(Spetzler)提出的以下分类:I型,硬脊膜动静脉瘘(AVF);II型,髓内球状AVM;III型,青少年型畸形;IV型,髓周AVF。一般来说,对于I型硬脊膜和IV型髓周AVF,完全闭塞瘘口是获得更好预后的关键。另一方面,对于II型球状和III型青少年型畸形,治疗的主要目标是功能保留,而非追求血管造影治愈。在这些情况下,减少分流可缓解临床症状。脊髓AVM的合理管理应始于神经学检查并了解血管构筑,这提供了指导干预适应证和方式的关键信息。最后,显微手术团队和血管内治疗团队的密切协作对于成功治疗至关重要。