Department of Neurosurgery, Ashikaga Red Cross Hospital, Ashikaga-City, Tochigi, Japan.
Neurol India. 2011 Sep-Oct;59(5):674-8. doi: 10.4103/0028-3886.86539.
Several malignant tumors and brain abscesses have similar magnetic resonance imaging (MRI) findings. Because the prognosis and treatment strategies differ among these disorders, accurate preoperative diagnosis is very significant. Recently, diffusion-weighted imaging (DWI) and calculation of apparent diffusion coefficients (ADCs) have been reported to be useful to differentiate between the two disorders.
MRI and DWI were performed in 37 patients: 13 with glioblastomas, 14 with metastatic tumors, 7 with malignant lymphomas, and 3 with brain abscesses. The minimum ADC value (ADC min ) and mean ADC value (ADC mean ) were taken into consideration.
Statistically significant differences were found in the enhanced lesions for ADC min and ADC mean between metastatic tumors and malignant lymphomas. The receiver operating characteristic analyses revealed no statistically significant differences among them. There were statistically significant differences in ADC mean in the cores of cystic lesions between brain abscesses and metastatic tumors or glioblastomas.
Our results suggest that evaluation using ADC values may facilitate differentiating metastatic tumors from malignant lymphomas, and also metastatic tumors or glioblastomas from brain abscesses.
一些恶性肿瘤和脑脓肿具有相似的磁共振成像（MRI）表现。由于这些疾病的预后和治疗策略不同，准确的术前诊断非常重要。最近，扩散加权成像（DWI）和表观扩散系数（ADC）的计算已被报道可用于区分这两种疾病。
对 37 例患者进行了 MRI 和 DWI 检查：13 例为胶质母细胞瘤，14 例为转移性肿瘤，7 例为恶性淋巴瘤，3 例为脑脓肿。考虑了最小 ADC 值（ADC min ）和平均 ADC 值（ADC mean ）。
转移性肿瘤和恶性淋巴瘤的强化病变的 ADC min 和 ADC mean 存在统计学差异。受试者工作特征分析显示它们之间无统计学差异。脑脓肿和转移性肿瘤或胶质母细胞瘤的囊性病变核心之间的 ADC mean 存在统计学差异。
我们的结果表明，使用 ADC 值评估可能有助于区分转移性肿瘤和恶性淋巴瘤，以及转移性肿瘤或胶质母细胞瘤与脑脓肿。
