Harris I D, Santoro N
Department of Obstetrics and Gynecology, University of Colorado Denver, Aurora, CO, USA.
Minerva Endocrinol. 2011 Sep;36(3):233-42.
The hypothalamic-pituitary-ovarian (HPO) axis goes through a series of complicated, but well coordinated changes as a women enters the menopausal transition. The reproductive consequences of these changes are obvious, but there are also a number of general health consequences as well. As our understanding of the complex inter-workings of the HPO axis evolves, we will be better able to predict menopausal events and create strategies and treatments to optimize women's health as the progress through the menopausal transition.
随着女性进入围绝经期过渡阶段，下丘脑 - 垂体 - 卵巢（HPO）轴会经历一系列复杂但协调良好的变化。这些变化对生殖的影响显而易见，但对整体健康也有诸多影响。随着我们对HPO轴复杂相互作用的理解不断深入，我们将更有能力预测绝经期事件，并制定策略和治疗方法，以在女性经历围绝经期过渡时优化其健康状况。
