Federal University of Pelotas, Brazil.
J Dent Res. 2012 Feb;91(2):179-84. doi: 10.1177/0022034511426573. Epub 2011 Oct 21.
Current challenges in adhesive dentistry include over-hydrophilic bonding formulations, which facilitate water percolation through the hybrid layer and result in unreliable bonded interfaces. This study introduces nanogel-modified adhesives as a way to control the material's hydrophobic character without changing the basic monomer formulation (keeping water-chasing capacity and operatory techniques unaltered). Nanogel additives of varied hydrophobicity were synthesized in solution, rendering 10- to 100-nm-sized particles. A model BisGMA/HEMA solvated adhesive was prepared (control), to which reactive nanogels were added. The increase in adhesive viscosity did not impair solvent removal by air-thinning. The degree of conversion in the adhesive was similar between control and nanogel-modified materials, while the bulk dry and, particularly, the wet mechanical properties were significantly improved through nanogel-based network reinforcement and reduced water solubility. As preliminary validation of this approach, short-term micro-tensile bond strengths to acid-etched and primed dentin were significantly enhanced by nanogel inclusion in the adhesive resins.
当前，黏结牙科领域面临的挑战包括超亲水黏结配方，该配方促使水通过混合层渗透，从而导致黏结界面不可靠。本研究提出了纳米凝胶改性黏结剂，它可以在不改变基础单体配方（保持水追逐能力和操作技术不变）的情况下控制材料的疏水性。通过溶液合成了具有不同疏水性的纳米凝胶添加剂，得到了 10-100nm 大小的颗粒。制备了一种模型 BisGMA/HEMA 溶剂化黏结剂（对照），并向其中添加了反应性纳米凝胶。黏结剂的黏度增加不会损害空气稀释去除溶剂的能力。与对照材料相比，纳米凝胶改性材料的黏结剂转化率相似，而通过基于纳米凝胶的网络增强和降低水溶性，其整体干燥性能，尤其是湿态机械性能得到了显著提高。作为该方法的初步验证，纳米凝胶的加入显著提高了酸蚀和预处理牙本质黏结后的短期微拉伸黏结强度。
