Picaud A, Nlome-Nze A R, Engongha-Beka T, Ogowet-Igumu N
Département de Gynécologie-Obstétrique, CHU, Libreville, Gabon.
Rev Fr Gynecol Obstet. 1990 Jun;85(6):379-81.
The authors summarize the case of diprosopic syncephalic joined twins diagnosed at 22 weeks of pregnancy by ultrasonography performed because of hydramnios. The rate of separation anomalies of monozygotic twins is assessed by a review of the literature: from 1 to twenty to fifty thousands for joined twins to 1 per cent fifty thousand to fifteen millions for diprosopus. The etiology is the result of a late division of the egg between D12 and D16. Often an encephalic diprosopic joined twins cause elevated levels of maternal serum alpha protein. Early ultrasonography permits to consider a vaginal therapeutic abortion.
作者总结了一例因羊水过多在妊娠22周时通过超声诊断出的双面联体双头联体双胎病例。通过文献回顾评估了单卵双胎的分离异常发生率:联体双胎为1/20000至1/50000,双面畸形为1/50000至1/15000000。病因是卵子在受精后第12至16天的晚期分裂。通常,脑双面联体双胎会导致母体血清甲胎蛋白水平升高。早期超声检查有助于考虑行阴道治疗性流产。