Zhu C Z, Norris J W
Stroke Research Unit, Sunnybrook Medical Centre, University of Toronto, Canada.
Stroke. 1990 Aug;21(8):1131-4. doi: 10.1161/01.str.21.8.1131.
Using Doppler ultrasonography, we evaluated the frequency and severity of carotid artery stenosis in 261 patients with carotid ischemic strokes, 813 patients with carotid transient ischemic attacks, 500 patients with asymptomatic neck bruits, and 500 controls. Most patients with strokes and transient ischemic attacks had no associated carotid artery disease (55% and 64%, respectively), and such patients without neck bruits were even more likely to be without carotid artery disease (69% and 77%, respectively). Carotid stenosis was more frequent and more likely to be severe in symptomatic than in asymptomatic patients (p less than 0.0002), even after adjusting for age and sex. Carotid stenosis is present in only a minority of patients with strokes and transient ischemic attacks, especially if neck bruits are absent, and the cause of the ischemic cerebral events in most of these patients remains unexplained.
我们使用多普勒超声检查评估了261例颈动脉缺血性卒中患者、813例颈动脉短暂性脑缺血发作患者、500例无症状颈部杂音患者以及500例对照者的颈动脉狭窄频率和严重程度。大多数卒中和短暂性脑缺血发作患者并无相关的颈动脉疾病（分别为55%和64%），而这些无颈部杂音的患者更有可能没有颈动脉疾病（分别为69%和77%）。即使在对年龄和性别进行校正之后，有症状患者的颈动脉狭窄在频率和严重程度上仍高于无症状患者（p<0.0002）。仅有少数卒中和短暂性脑缺血发作患者存在颈动脉狭窄，尤其是在无颈部杂音的情况下，而这些患者中大多数缺血性脑事件的病因仍无法解释。
