Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles, CA, USA.
Rheum Dis Clin North Am. 2011 Aug;37(3):351-63, v. doi: 10.1016/j.rdc.2011.07.005.
Controversies regarding appropriate use of vitamin D and calcium are predominately related to the extraskeletal effects. Calcium and vitamin D are essential for bone health. The concerns regarding calcium and cardiovascular complications are inconclusive at best, and do not warrant a change in our approach to supplementation at this time. A growing body of literature exists suggesting that additional vitamin D may have numerous benefits, although more study needs to be done. Further prospective trials would provide insight into the potential advantages that increased vitamin D supplementation could provide.
关于维生素 D 和钙的合理使用存在争议,主要与骨骼外作用有关。钙和维生素 D 是骨骼健康所必需的。关于钙与心血管并发症之间的关系,目前的研究结果尚无定论,因此我们现阶段不必改变钙和维生素 D 的补充方式。越来越多的文献表明,额外补充维生素 D 可能有诸多益处,但还需要更多的研究。进一步的前瞻性试验将提供更多关于增加维生素 D 补充可能带来的潜在益处的信息。