University of Manitoba, Richardson Centre for Functional Foods and Nutraceuticals, Winnipeg, MB R3T 2N2, Canada.
Appl Physiol Nutr Metab. 2011 Dec;36(6):811-20. doi: 10.1139/h11-101. Epub 2011 Oct 25.
The objective was to evaluate the effects of whole and fractionated yellow peas on circulating lipids, glucose and insulin levels, energy expenditure, and body composition, as well as to assess their prebiotic actions in Golden Syrian hamsters. Forty-five hamsters consumed a hypercholesterolemic diet for 28 days, then were randomly assigned to 1 of 3 groups: control (CON), whole pea flour (WPF), and fractionated pea flour (hulls only) (FPF). WPF and FPF were incorporated into the diets, replacing 10% of the cornstarch. WPF and FPF feeding produced negligible effects on circulating cholesterol and triglyceride levels. However, both WPF (56.76 ± 9.22 pmol·L⁻¹, p = 0.002) and FPF (89.27 ± 19.82 pmol·L⁻¹, p = 0.032) reduced circulating insulin levels compared with the CON group (131.70 ± 17.70 pmol·L⁻¹). Moreover, FPF decreased (p = 0.03) circulating glucose levels (6.26 ± 0.51 mmol·L⁻¹) compared with CON (8.27 ± 0.81 mmol·L⁻¹). Energy expenditure analysis revealed that hamsters consuming WPF demonstrated a higher (p = 0.036) oxygen consumption (2.00 ± 0.31 mL O₂·g⁻¹ lean body mass) vs. the CON group (1.56 ± 0.089 mL O₂·g⁻¹ lean body mass). Analysis of caecal digesta showed that WPF produced shifts in the abundance of microbial taxa with the most predominant changes occurring within the phylum Firmicutes. Yellow peas and their constituents should be investigated as future functional food ingredients that help prevent and manage lifestyle-related diseases such as diabetes and obesity.
目的是评估全豌豆和豌豆分离粉（仅豆壳）对循环脂质、血糖和胰岛素水平、能量消耗和身体成分的影响，并评估它们在金黄地鼠中的益生元作用。45 只金黄地鼠食用高胆固醇饮食 28 天，然后随机分为 3 组：对照组（CON）、全豌豆粉（WPF）和豌豆分离粉（仅豆壳）（FPF）。WPF 和 FPF 被纳入饮食中，替代 10%的玉米淀粉。WPF 和 FPF 的喂养对循环胆固醇和甘油三酯水平几乎没有影响。然而，与 CON 组相比，WPF（56.76±9.22 pmol·L⁻¹，p=0.002）和 FPF（89.27±19.82 pmol·L⁻¹，p=0.032）均降低了循环胰岛素水平。此外，与 CON 组相比，FPF 降低了循环血糖水平（6.26±0.51 mmol·L⁻¹，p=0.03）。能量消耗分析表明，食用 WPF 的金黄地鼠表现出更高的耗氧量（2.00±0.31 mL O₂·g⁻¹ 去脂体重）（p=0.036），而 CON 组为 1.56±0.089 mL O₂·g⁻¹ 去脂体重。盲肠内容物分析表明，WPF 导致微生物分类群的丰度发生变化，其中最主要的变化发生在厚壁菌门。豌豆及其成分应作为未来的功能性食品成分进行研究，以帮助预防和管理与生活方式相关的疾病，如糖尿病和肥胖症。
