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播散型戈登分枝杆菌感染 1 例囊性纤维化患儿

Disseminated Mycobacterium gordonae infection in a child with cystic fibrosis.

机构信息

Department of Respiratory Paediatrics, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.

出版信息

Pediatr Pulmonol. 2012 May;47(5):517-8. doi: 10.1002/ppul.21574. Epub 2011 Oct 25.

DOI:10.1002/ppul.21574
PMID:22028301
Abstract

A 4-year-old girl with cystic fibrosis (CF) presented with unrelenting pyrexia commencing shortly after flushing of the central venous catheter (CVC). Mycobacterium gordonae was subsequently isolated from bronchoalveolar lavage, gastric washings, and lung biopsy. While this case most likely represents central line infection by a non-tuberculous mycobacterial (NTM) species, it is difficult to state this definitively in the absence of positive cultures from the CVC. We suggest that infection with NTM should always be considered in CF patients with indwelling devices and unexplained fever.

摘要

一位 4 岁的女孩患有囊性纤维化 (CF),在中央静脉导管 (CVC) 冲洗后不久出现持续发热。随后从支气管肺泡灌洗、胃洗液和肺活检中分离出戈登分枝杆菌。虽然本例很可能代表非结核分枝杆菌 (NTM) 引起的中心导管感染,但由于 CVC 无阳性培养,很难明确诊断。我们建议,对于有留置装置和不明原因发热的 CF 患者,应始终考虑 NTM 感染。

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