Sci Signal. 2011 Oct 25;4(196):eg9. doi: 10.1126/scisignal.2002601.
The extracellular signal-regulated kinase (ERK) pathway is one of the superfamily of mitogen-activated protein kinase pathways. Signals transmitted by this kinase cascade activate a pair of related proteins, ERK1 and ERK2. Research published in Science Signaling shows that, despite the wealth of knowledge about this pathway, previously unknown functions continue to be discovered and additional components in this pathway continue to be identified. Thus, we are continuing to learn the plays and recruit the players in the game that is ERK signaling.
细胞外信号调节激酶（ERK）途径是丝裂原活化蛋白激酶途径超家族之一。该激酶级联传递的信号激活一对相关蛋白，ERK1 和 ERK2。Science Signaling 上发表的研究表明，尽管人们对这条通路有丰富的了解，但仍在不断发现以前未知的功能，并不断鉴定该通路中的其他成分。因此，我们还在继续了解 ERK 信号通路中的“游戏”规则并确定其中的“角色”。
