Chowdhury F H, Haque M R, Islam M S, Sarker Mh, Kawsar Ka, Sarker Ac
Department of Neurosurgery, Dhaka Medical College Hospital, Dhaka, Bangladesh .
Asian J Neurosurg. 2010 Jul;5(2):10-8.
Patient presenting as a case of Temporal Lobe Epilepsy (TLE) are usually resistant to antiepileptic drugs and surgery is the treatment of choice. This type of epilepsy may be due to Mesial Temporal Sclerosis (MTS), tumors [i.e. low grade glioma, Arterio-Venous Malformation (AVM) etc], trauma, infection (Tuberculosis) etc. Here we report five cases of surgically treated TLE that were due to a MTS, MTS with arachnoid cyst, low grade ganglioglioma, high grade ganglioglioma and a tuberculoma in the department of neurosurgery, Dhaka Medical College Hospital and Islami Bank Central Hospital, Dhaka, Bangladesh from August 2009 to February 2010. In all cases the only presenting symptoms was complex partial seizures (psychomotor epilepsy) for which all underwent scalp EEG (Electro Encephalogram) and MRI (Magnetic Resonance Imaging) of Brain. All patients were managed by amygdalohippocampectomy plus standard anterior lobectomy. One patient with high grade ganglioglioma recurred within two months of operation and expired within five months. The rest of the cases are seizure and disease free till the last follow up.
表现为颞叶癫痫（TLE）的患者通常对抗癫痫药物耐药，手术是首选治疗方法。这种类型的癫痫可能由内侧颞叶硬化（MTS）、肿瘤[如低级别胶质瘤、动静脉畸形（AVM）等]、创伤、感染（结核病）等引起。在此，我们报告2009年8月至2010年2月期间，在孟加拉国达卡医学院医院神经外科和达卡伊斯兰银行中央医院，因MTS、伴有蛛网膜囊肿的MTS、低级别节细胞胶质瘤、高级别节细胞胶质瘤和结核瘤而接受手术治疗的5例TLE病例。所有病例唯一的表现症状均为复杂部分性发作（精神运动性癫痫），为此所有患者均接受了头皮脑电图（EEG）和脑部磁共振成像（MRI）检查。所有患者均接受了杏仁核海马切除术加标准前叶切除术。1例高级别节细胞胶质瘤患者术后2个月内复发，5个月内死亡。其余病例直至最后一次随访时均无癫痫发作且病情无进展。
