[麦角固醇生物合成改变的酿酒酵母突变体中的固醇水平]
[Sterol level in Saccharomyces cerevisiae mutants with altered ergosterol biosynthesis].
作者信息
Mikhaĭlova N P, Ogorodnikova T E, V'iunov K A
出版信息
Prikl Biokhim Mikrobiol. 1990 May-Jun;26(3):360-3.
PMID:2202986
Abstract
The sterol content in Saccharomyces cerevisiae mutants defective in the synthesis of cyclic ergosterol precursors has been studied. It was found that strains with mutational blocks involving the stages of zymosterol side chain methylation at C24 and delta 8----delta 7 isomerization accumulated twice more sterols as compared to parent strains. Regulation of the ergosterol biosynthesis is discussed.
摘要
对酿酒酵母中参与环状麦角甾醇前体合成缺陷的突变体的甾醇含量进行了研究。结果发现，与亲本菌株相比，在24位酵母甾醇侧链甲基化和δ8→δ7异构化阶段存在突变阻断的菌株积累的甾醇多两倍。文中还讨论了麦角甾醇生物合成的调控。
Zotero 插件