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本文引用的文献

1
Typologies of cannabis users and associated characteristics relevant for public health: a latent class analysis of data from a nationally representative Canadian adult survey.大麻使用者的类型学及其与公共卫生相关的特征:基于全国代表性加拿大成人调查数据的潜在类别分析。
Int J Methods Psychiatr Res. 2010 Jun;19(2):110-24. doi: 10.1002/mpr.307.
2
High-potency cannabis and the risk of psychosis.高效力大麻与精神病风险
Br J Psychiatry. 2009 Dec;195(6):488-91. doi: 10.1192/bjp.bp.109.064220.
3
Toward a more parsimonious approach to drug recognition expert evaluations.迈向更简约的药物识别专家评估方法。
Traffic Inj Prev. 2009 Dec;10(6):513-8. doi: 10.1080/15389580903191617.
4
Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study.子宫内大麻暴露影响胎儿生长轨迹:生育队列研究。
J Am Acad Child Adolesc Psychiatry. 2009 Dec;48(12):1173-81. doi: 10.1097/CHI.0b013e3181bfa8ee.
5
Adverse health effects of non-medical cannabis use.非医用大麻使用对健康的不良影响。
Lancet. 2009 Oct 17;374(9698):1383-91. doi: 10.1016/S0140-6736(09)61037-0.
6
Assessing evidence for a causal link between cannabis and psychosis: a review of cohort studies.评估大麻与精神病之间因果关联的证据:队列研究综述。
Int J Drug Policy. 2010 Jan;21(1):10-9. doi: 10.1016/j.drugpo.2009.09.001. Epub 2009 Sep 26.
7
The effect of cannabis compared with alcohol on driving.大麻与酒精对驾驶影响的比较。
Am J Addict. 2009 May-Jun;18(3):185-93. doi: 10.1080/10550490902786934.
8
Is driving under the influence of cannabis becoming a greater risk to driver safety than drink driving? Findings from a longitudinal study.吸食大麻后驾车对驾驶员安全构成的风险是否正变得比酒后驾车更大?一项纵向研究的结果。
Accid Anal Prev. 2008 Jul;40(4):1345-50. doi: 10.1016/j.aap.2008.02.005. Epub 2008 Mar 18.
9
Cannabis use and later life outcomes.大麻使用与晚年生活结局。
Addiction. 2008 Jun;103(6):969-76; discussion 977-8. doi: 10.1111/j.1360-0443.2008.02221.x.
10
Illicit drug use and neonatal outcomes: a critical review.非法药物使用与新生儿结局:一项批判性综述。
Obstet Gynecol Surv. 2007 Nov;62(11):749-57. doi: 10.1097/01.ogx.0000286562.31774.76.

加拿大低风险大麻使用指南(LRCUG):证据和建议的叙述性综述。

Lower Risk Cannabis use Guidelines for Canada (LRCUG): a narrative review of evidence and recommendations.

机构信息

Centre for Applied Research in Mental Health and Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, BC.

出版信息

Can J Public Health. 2011 Sep-Oct;102(5):324-7. doi: 10.1007/BF03404169.

DOI:10.1007/BF03404169
PMID:22032094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6973752/
Abstract

OBJECTIVES

More than one in ten adults--and about one in three young adults--report past year cannabis use in Canada. While cannabis use is associated with a variety of health risks, current policy prohibits all use, rather than adopting a public health approach focusing on interventions to address specific risks and harms as do policies for alcohol. The objective of this paper was to develop 'Lower Risk Cannabis Use Guidelines' (LRCUG) based on research evidence on the adverse health effects of cannabis and factors that appear to modify the risk of these harms.

METHODS

Relevant English-language peer-reviewed publications on health harms of cannabis use were reviewed and LRCUG were drafted by the authors on the basis of a consensus process.

SYNTHESIS

The review suggested that health harms related to cannabis use increase with intensity of use although the risk curve is not well characterized. These harms are associated with a number of potentially modifiable factors related to: frequency of use; early onset of use; driving after using cannabis; methods and practices of use and substance potency; and characteristics of specific populations. LRCUG recommending ways to reduce risks related to cannabis use on an individual and population level--analogous to 'Low Risk Drinking Guidelines' for alcohol--are presented.

CONCLUSIONS

Given the prevalence and age distribution of cannabis use in Canada, a public health approach to cannabis use is overdue. LRCUG constitute a potentially valuable tool in facilitating a reduction of health harms from cannabis use on a population level.

摘要

目的

在加拿大,超过十分之一的成年人——约三分之一的年轻人——报告过去一年有大麻使用史。虽然大麻使用与各种健康风险有关,但现行政策禁止所有使用,而不是像对待酒精那样采取公共卫生方法,侧重于针对特定风险和危害的干预措施。本文的目的是根据有关大麻使用对健康的不良影响的研究证据,并根据似乎可以改变这些危害风险的因素,制定“低风险大麻使用指南”(LRCUG)。

方法

审查了有关大麻使用对健康危害的相关英语同行评议文献,并由作者根据共识过程起草了 LRCUG。

综合

综述表明,与大麻使用相关的健康危害随着使用强度的增加而增加,尽管风险曲线的特征尚不明确。这些危害与一些潜在的可改变的因素有关,包括:使用频率;使用大麻的起始年龄;使用大麻后驾驶;使用方法和做法以及物质效力;以及特定人群的特征。提出了降低与大麻使用相关的个体和人群风险的 LRCUG——类似于酒精的“低风险饮酒指南”。

结论

鉴于加拿大大麻使用的流行率和年龄分布,大麻使用的公共卫生方法已经过时。LRCUG 构成了在人群层面上减少大麻使用对健康危害的潜在有价值的工具。