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Assessing the prevalence of non-medical prescription opioid use in the Canadian general adult population: evidence of large variation depending on survey questions used.评估加拿大普通成年人群中非医疗处方类阿片类药物使用的流行率:使用不同的调查问题会产生很大差异的证据。
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本文引用的文献

1
Characteristics and correlates of men and women with prescription opioid dependence.男性和女性处方阿片类药物依赖者的特征和相关性。
Addict Behav. 2011 Aug;36(8):829-34. doi: 10.1016/j.addbeh.2011.03.013. Epub 2011 Mar 25.
2
Assessing the prevalence of nonmedical prescription opioid use in the general Canadian population: methodological issues and questions.评估加拿大普通人群中非医疗处方类阿片类药物使用的流行率:方法学问题与疑问。
Can J Psychiatry. 2010 Sep;55(9):606-9. doi: 10.1177/070674371005500909.
3
Gender and prescription opioids: findings from the National Survey on Drug Use and Health.性别与处方类阿片:来自全国药物使用与健康调查的结果。
Addict Behav. 2010 Nov;35(11):1001-7. doi: 10.1016/j.addbeh.2010.06.018. Epub 2010 Jun 22.
4
Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone.在长效羟考酮推出前后,阿片类镇痛药的处方和相关死亡率。
CMAJ. 2009 Dec 8;181(12):891-6. doi: 10.1503/cmaj.090784. Epub 2009 Dec 7.
5
Deaths related to the use of prescription opioids.与使用处方阿片类药物相关的死亡。
CMAJ. 2009 Dec 8;181(12):881-2. doi: 10.1503/cmaj.091791. Epub 2009 Dec 7.
6
Non-response bias in alcohol and drug population surveys.酒精和毒品人群调查中的无应答偏差。
Drug Alcohol Rev. 2009 Nov;28(6):648-57. doi: 10.1111/j.1465-3362.2009.00077.x.
7
How many people in Canada use prescription opioids non-medically in general and street drug using populations?加拿大有多少人在一般情况下和在使用街头毒品的人群中非医疗目的使用处方类阿片?
Can J Public Health. 2009 Mar-Apr;100(2):104-8. doi: 10.1007/BF03405516.
8
Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions.非医用阿片类药物使用/依赖与精神障碍之间的关联途径:来自酒精及相关疾病全国流行病学调查的结果
Drug Alcohol Depend. 2009 Jul 1;103(1-2):16-24. doi: 10.1016/j.drugalcdep.2009.01.019. Epub 2009 May 2.
9
Gender and non-medical use of prescription opioids: results from a national US survey.性别与处方阿片类药物的非医疗用途:美国一项全国性调查的结果
Addiction. 2008 Feb;103(2):258-68. doi: 10.1111/j.1360-0443.2007.02056.x. Epub 2007 Nov 27.
10
Potential influences on initiation and persistence of extramedical prescription pain reliever use in the US population.对美国人群使用非医疗处方止痛药的起始和持续使用的潜在影响。
Clin J Pain. 2006 Nov-Dec;22(9):776-83. doi: 10.1097/01.ajp.0000210926.41406.2c.

安大略省成年人处方阿片类药物的非医疗用途:来自 2008/2009 年 CAMH 监测的数据。

Non-medical use of prescription opioids among Ontario adults: data from the 2008/2009 CAMH Monitor.

机构信息

Centre for Addiction and Mental Health (CAMH), Toronto, ON.

出版信息

Can J Public Health. 2011 Sep-Oct;102(5):330-5. doi: 10.1007/BF03404171.

DOI:10.1007/BF03404171
PMID:22032096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6973684/
Abstract

OBJECTIVE

There are indications that non-medical prescription opioid analgesics use (NMPOU) in the general population has increased in Canada in recent years; however, existing estimates have limitations. Thus our objectives are to determine prevalence and associated demographics of 1) prescription opioid analgesics (PO) use, 2) NMPOU, and 3) use of PO for intoxication purposes in the adult population in Ontario.

METHODS

Prevalence and the associations between sex, age, region, income, cigarette smoking, binge drinking, cannabis use and psychological distress with the above-noted types of PO use were assessed using data from the 2008 and 2009 samples (n = 2030) of the CAMH Monitor. The statistical significance of the associations for all types of PO use was tested through bivariate associations using chi-square tests, and a two-step logistic regression was performed to test if demographics are associated with NMPOU.

RESULTS

The prevalence of PO use was 21.3% (95% CI 19.1-23.4), and the prevalence of NMPOU was 2.0% (95% CI 1.2-2.8) of Ontario adults. There were no significant differences between men and women for either PO use or NMPOU. Bivariate associations indicated that NMPOU was associated with tobacco and cannabis use and psychological distress in men. Logistic regression showed a significant association between NMPOU and each of age, cannabis use, and psychological distress in men.

DISCUSSION

NMPOU is an emerging epidemic in Canada across all income and age groups, and is associated with other substance use and mental health problems. Improved survey designs are required for more accurate population estimates of NMPOU.

摘要

目的

有迹象表明,近年来加拿大普通人群中非医疗处方类阿片类镇痛药的使用(NMPOU)有所增加;然而,现有的估计存在局限性。因此,我们的目的是确定安大略省成年人群中 1)处方类阿片类镇痛药(PO)的使用、2)NMPOU 和 3)PO 用于中毒的流行率和相关人口统计学特征。

方法

使用来自 2008 年和 2009 年 CAMH Monitor 样本(n=2030)的数据,评估了性别、年龄、地区、收入、吸烟、狂饮、大麻使用和心理困扰与上述 PO 使用类型之间的相关性。使用卡方检验进行了双变量关联,以测试所有类型 PO 使用的关联的统计学意义,还进行了两步逻辑回归,以测试人口统计学是否与 NMPOU 相关。

结果

PO 使用的流行率为 21.3%(95%CI 19.1-23.4),安大略省成年人 NMPOU 的流行率为 2.0%(95%CI 1.2-2.8)。男性和女性在 PO 使用或 NMPOU 方面均无显著差异。双变量关联表明,NMPOU 与男性的烟草和大麻使用以及心理健康问题有关。逻辑回归显示,NMPOU 与男性的年龄、大麻使用和心理健康问题均存在显著关联。

讨论

NMPOU 在加拿大是一种正在出现的全年龄段、各收入群体的流行现象,并且与其他物质使用和心理健康问题有关。需要改进调查设计,以更准确地估计 NMPOU 的人群流行率。