Løfors K T, Høvding G, Viksmoen L, Aasved H, Bergaust B, Bulie T
Eye Department, University Hospital, Trondheim, Norway.
Acta Ophthalmol (Copenh). 1990 Jun;68(3):323-6. doi: 10.1111/j.1755-3768.1990.tb01931.x.
The 12 h IOP control achieved by a single application of a newly developed ophthalmic solution containing 0.5% timolol and 2% resp. 4% pilocarpine was compared with that obtained by 1 dose of timolol 0.5% alone in 33 patients with manifest open angle glaucoma or ocular hypertension. The combined solutions gave a significantly better 12 h IOP control, evidenced by both a reduced mean diurnal IOP and a decreased frequency of larger pressure peaks.
在33例显性开角型青光眼或高眼压症患者中，将一种新开发的含有0.5%噻吗洛尔和分别为2%及4%毛果芸香碱的眼科溶液单次应用所实现的12小时眼压控制，与单独使用一剂0.5%噻吗洛尔所获得的眼压控制进行了比较。联合溶液在12小时眼压控制方面效果显著更好，这表现为平均日间眼压降低以及较大压力峰值的频率减少。
