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超高精神病风险人群中自杀风险因素的流行情况:服务审计。

Prevalence of suicide risk factors in people at ultra-high risk of developing psychosis: a service audit.

机构信息

Psychosis Research Unit (PRU) Early Detection and Intervention Team (EDIT), Greater Manchester West Mental Health Foundation NHS Trust, Bury New Road, Prestwich, Manchester, UK.

出版信息

Early Interv Psychiatry. 2011 Nov;5(4):375-80. doi: 10.1111/j.1751-7893.2011.00302.x.

Abstract

BACKGROUND

Little data is available on the prevalence of suicide risk factors in people at ultra-high risk (UHR) of developing psychosis.

AIM

The aim of this study was to provide an estimate of the cross-sectional prevalence of possible suicide risk factors in those attending a routine clinical service for people at UHR of developing psychosis.

METHODS

For all patients in treatment (n=34) over a 4-week period, levels of suicidal ideation and depression upon entry to the service were assessed by auditing intake scores on the Beck Depression Inventory, second edition. Level of engagement with services, social isolation, substance and alcohol misuse, ready access to means, current suicidal ideation, previous suicide attempts, current or previous self-harm, expressions of concern from others, depression, agitation, hopelessness, worthlessness, suspiciousness and fears of mental disintegration were all assessed by case note review and interview with the treating clinician.

RESULTS

There was a high prevalence of at least mild suicidal ideation (58.8%, n=20) and severe depressed mood (47%, n=16) in this client group at point of entry to the service. Seven people (20.6%) had engaged in serious self-harm (including attempted suicide) during the time they were in contact with the service. Forty-seven per cent (n=16) reported at least 27 suicide attempts between them; the mean number of attempts being 1.69 (standard deviation=1.08).

CONCLUSION

Suicide risk was high in this small sample of people at UHR of developing psychosis. Controlled research with larger samples and better methodology is urgently required to inform legal, ethical and scientific debates surrounding this group.

摘要

背景

关于处于精神病发病极高风险(UHR)的人群中自杀风险因素的流行率,数据很少。

目的

本研究旨在提供在常规临床服务中处于精神病发病极高风险的人群中,目前自杀风险因素的横断面流行率的估计值。

方法

在 4 周的时间内,对参加精神分裂症发病极高风险人群常规临床服务的所有治疗患者(n=34),通过审核贝克抑郁量表第二版的入院分数来评估自杀意念和抑郁程度。通过病例记录回顾和与主治临床医生的访谈,评估与服务的接触程度、社会隔离、物质和酒精滥用、获取手段的便利性、当前的自杀意念、既往自杀企图、当前或既往的自我伤害、他人的关注表达、抑郁、激越、绝望、无价值感、多疑和对精神分裂的恐惧等。

结果

在服务进入时,该患者群体中至少有轻度自杀意念(58.8%,n=20)和严重抑郁情绪(47%,n=16)的患病率很高。七人(20.6%)在与服务机构接触期间曾严重自残(包括自杀企图)。47%(n=16)报告至少有 27 次自杀企图,他们的平均自杀企图次数为 1.69(标准差=1.08)。

结论

在这个处于精神病发病极高风险的小样本人群中,自杀风险很高。需要进行有更大样本和更好方法的对照研究,为这一群体的法律、伦理和科学辩论提供信息。

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