Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.
J Nat Prod. 2011 Nov 28;74(11):2472-6. doi: 10.1021/np200678n. Epub 2011 Oct 27.
Four new phenolic glycosides, saccharumosides A-D (1-4), along with eight known phenolic glycosides, were isolated from the bark of sugar maple (Acer saccharum). The structures of 1-4 were elucidated on the basis of spectroscopic data analysis. All compounds isolated were evaluated for cytotoxicity effects against human colon tumorigenic (HCT-116 and Caco-2) and nontumorigenic (CCD-18Co) cell lines.
从糖枫(Acer saccharum)树皮中分离得到了 4 个新的酚糖苷,即 saccharumosides A-D(1-4),以及 8 个已知的酚糖苷。基于光谱数据分析,确定了 1-4 的结构。所有分离得到的化合物均对人结肠肿瘤细胞系(HCT-116 和 Caco-2)和非肿瘤细胞系(CCD-18Co)进行了细胞毒性作用评估。