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糖枫(Acer saccharum)树皮中的酚糖苷。

Phenolic glycosides from sugar maple (Acer saccharum) bark.

机构信息

Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.

出版信息

J Nat Prod. 2011 Nov 28;74(11):2472-6. doi: 10.1021/np200678n. Epub 2011 Oct 27.

Abstract

Four new phenolic glycosides, saccharumosides A-D (1-4), along with eight known phenolic glycosides, were isolated from the bark of sugar maple (Acer saccharum). The structures of 1-4 were elucidated on the basis of spectroscopic data analysis. All compounds isolated were evaluated for cytotoxicity effects against human colon tumorigenic (HCT-116 and Caco-2) and nontumorigenic (CCD-18Co) cell lines.

摘要

从糖枫(Acer saccharum)树皮中分离得到了 4 个新的酚糖苷,即 saccharumosides A-D(1-4),以及 8 个已知的酚糖苷。基于光谱数据分析,确定了 1-4 的结构。所有分离得到的化合物均对人结肠肿瘤细胞系(HCT-116 和 Caco-2)和非肿瘤细胞系(CCD-18Co)进行了细胞毒性作用评估。

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