Thiem A, Attmann T, Cremer J
Klinik für Herz- und Gefäßchirurgie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Haus 18, 24105, Kiel, Deutschland.
Herz. 2011 Dec;36(8):669-76. doi: 10.1007/s00059-011-3532-6.
Coronary artery bypass grafting (CABG), a modern and safe procedure, is considered the therapy of choice in the care of patients with multi-vessel disease. The 3-year results of the SYNTAX trial not only showed surgical advantages in terms of repeat revascularisation, but the results also demonstrated significant surgical benefit for myocardial infarction and survival rates. More differentiated analyses showed distinct disadvantages in percutaneous coronary intervention (PCI) associated with the greater complexity of coronary pathology. PCI tends to be a comparable therapeutic option only in certain cases of left main stem lesions or multi-vessel disease. The findings from the SYNTAX study herald a new era in the treatment of coronary heart disease in which, as recommended in the updated guidelines issued by the EACTS/ESC in 2010, the interventionalist and the surgeon, working closely together as a"heart team", provide a sound therapy plan for affected patients.
冠状动脉旁路移植术（CABG）是一种现代且安全的手术，被视为多支血管病变患者治疗的首选方法。SYNTAX试验的3年结果不仅显示出手术在再次血运重建方面的优势，而且结果还表明手术对心肌梗死和生存率有显著益处。更细致的分析显示，经皮冠状动脉介入治疗（PCI）存在明显劣势，这与冠状动脉病变的复杂性增加有关。PCI往往仅在某些左主干病变或多支血管病变的情况下才是一种可比较的治疗选择。SYNTAX研究的结果开创了冠心病治疗的新纪元，正如欧洲心胸外科学会（EACTS）/欧洲心脏病学会（ESC）在2010年发布的更新指南中所建议的那样，介入专家和外科医生作为一个“心脏团队”密切合作，为受影响的患者提供完善的治疗方案。
