Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
Br J Surg. 2011 Dec;98(12):1775-83. doi: 10.1002/bjs.7648. Epub 2011 Aug 25.
Complication management appears to be of vital importance to differences in survival following surgery between surgical units. Failure-to-rescue (FTR) rates have not yet distinguished surgical from general medical complications. The aim of this study was to assess whether variability exists in FTR rates after reoperation for serious surgical complications following colorectal cancer resections in England.
The Hospital Episode Statistics (HES) database was used to identify patients undergoing primary resection for colorectal cancer between 2000 and 2008 in English National Health Service (NHS) trusts. Units were ranked into quintiles according to overall risk-adjusted mortality. Highest and lowest mortality quintiles were compared with respect to reoperation rates and FTR-surgical (FTR-S) rates. FTR-S was defined as the proportion of patients with an unplanned reoperation who died within the same admission.
Some 144 542 patients undergoing resection for colorectal cancer in 150 English NHS trusts were included. On ranking according to risk-adjusted mortality, rates varied significantly between lowest and highest mortality quintiles (5·4 and 9·3 per cent respectively; P = 0·029). Lowest and highest mortality quintiles had equivalent adjusted reoperation rates (both 4·8 per cent; P = 0·211). FTR-S rates were significantly higher at units within the worst mortality quintile (16·8 versus 11·1 per cent; P = 0·002).
FTR-S rates differed significantly between English colorectal units, highlighting variability in ability to prevent death in this high-risk group. This variability may represent differences in serious surgical complication management. FTR-S represents a readily collectable marker of surgical complication management that is likely to be applicable to other surgical specialties.
并发症管理对于手术单位之间手术患者生存率的差异似乎至关重要。失败救援(FTR)率尚未区分手术和一般医疗并发症。本研究旨在评估英国结直肠癌切除术后严重手术并发症再次手术后 FTR 率是否存在差异。
使用医院病例统计(HES)数据库,确定 2000 年至 2008 年期间在英格兰国家卫生服务(NHS)信托机构接受原发性结直肠癌切除术的患者。根据总体风险调整死亡率,将单位分为五分位数。比较最高和最低死亡率五分位数的再手术率和 FTR-手术(FTR-S)率。FTR-S 定义为计划外再次手术患者中在同一入院期间死亡的比例。
在 150 个英国 NHS 信托机构中,有 144542 名患者接受结直肠癌切除术。根据风险调整死亡率进行排名,死亡率在最低和最高死亡率五分位数之间差异显著(分别为 5.4%和 9.3%;P=0.029)。最低和最高死亡率五分位数的调整再手术率相同(均为 4.8%;P=0.211)。死亡率最差的五分位数内的单位 FTR-S 率明显更高(分别为 16.8%和 11.1%;P=0.002)。
英国结直肠单位之间的 FTR-S 率存在显著差异,突出了该高风险人群预防死亡能力的差异。这种差异可能代表严重手术并发症管理的差异。FTR-S 是一种易于收集的手术并发症管理标志物,可能适用于其他外科专业。