Franz R, Hartman J, Wright M
The Vascular and Vein Center at Grant Medical Center, Columbia, OH, USA.
J Cardiovasc Surg (Torino). 2011 Aug;52(4):567-77.
This retrospective study compares outcomes according to anesthesia technique of a consecutive series of 48 endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAAs) performed by one vascular surgeon at a single institution over a five-year period.
Demographic, pre-procedure, procedure-related, recovery room, surgical unit, and hospital outcome variables were extracted and compared between patients receiving general or regional anesthesia and those receiving monitored anesthesia care (MAC) with local anesthesia.
Eighteen (37.5%) patients received general or regional anesthesia and 30 (62.5%) patients received MAC with local anesthesia. No statistically significant differences in demographics or pre-procedure variables were calculated between study groups. Conversion to open repair was not required, no intraoperative complications occurred, and conversion from MAC with local anesthesia to general anesthesia was not required. The only significant differences calculated were in length of anesthesia (P=0.001, power 0.962) and time to ambulation (P=0.004, power 0.871), with significantly lower median times in the MAC and local anesthesia groups. Other than one (2.1%) patient in the MAC with local anesthesia group whose death was related to history of severe coronary disease, no other acute medical complications occurred.
The results of this study suggest that use of MAC with local anesthesia during EVAR of AAAs is comparable to general and regional anesthesia in terms of safety and efficacy. Furthermore, MAC with local anesthesia confers additional outcome benefits versus general and regional anesthesia, as it is less invasive, offers greater hemodynamic stability, and enables better communication with the patient.
本回顾性研究比较了在一家机构中,由一位血管外科医生在五年期间连续进行的48例腹主动脉瘤(AAA)血管内修复术(EVAR)中,不同麻醉技术的效果。
提取了人口统计学、术前、手术相关、恢复室、外科病房和医院结局变量,并在接受全身或区域麻醉的患者与接受局部麻醉监护麻醉(MAC)的患者之间进行比较。
18例(37.5%)患者接受全身或区域麻醉,30例(62.5%)患者接受局部麻醉监护麻醉(MAC)。研究组之间在人口统计学或术前变量方面未计算出统计学上的显著差异。无需转为开放修复,未发生术中并发症,也无需从局部麻醉监护麻醉(MAC)转为全身麻醉。计算出的唯一显著差异在于麻醉时长(P = 0.001,检验效能0.962)和下床活动时间(P = 0.004,检验效能0.871),局部麻醉监护麻醉(MAC)组的中位时间显著更短。除局部麻醉监护麻醉(MAC)组中有1例(2.1%)患者死亡与严重冠心病病史有关外,未发生其他急性医疗并发症。
本研究结果表明,在腹主动脉瘤血管内修复术(EVAR)期间使用局部麻醉监护麻醉(MAC)在安全性和有效性方面与全身和区域麻醉相当。此外,与全身和区域麻醉相比,局部麻醉监护麻醉(MAC)在结局方面具有额外优势,因为它侵入性更小,血流动力学稳定性更高,并且能更好地与患者沟通。