Hsiu H, Hsu C L, Wu T L
Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, ROC.
Proc Inst Mech Eng H. 2011 Jun;225(6):575-83. doi: 10.1177/0954411910396288.
The blood pressure (BP) waveform is suggested to reflect the whole-body blood supply distribution, but its non-invasive assessment is not sufficiently user friendly for practical applications. The present authors studied the correlation between BP and photoplethysmography (PPG) waveforms, with the aim of determining the optimal range for contact pressure stimulation (PS) to produce a reliable transfer function in their harmonic parameters.
Finger PPG and radial-artery BP signals were measured simultaneously and noninvasively on healthy volunteers (n = 45). PS of 0-200 mmHg was applied to the finger, and 1 min data sequences were recorded. In frequency-domain analysis, linear regression was applied to the calculated amplitude ratios or the first five harmonics between BP and PPG waveforms.
In the 60 mmHg-PS group, the BP-PPG regression of amplitude ratios was highest, and the agreements between them were also the best verified by Bland-Altman analysis.
In the present study, frequency-domain analysis was performed to study the correlation between BP and PPG waveforms. Differences in pressure-induced-vasodilation responses underlie the different BP-PPG waveform correlations obtained by applying different PSs. The non-invasively derived PPG parameters might help to provide an easier method to acquire the radial-artery BP waveform, and hence broaden the application of BP waveform analysis.
血压（BP）波形被认为能反映全身血液供应分布情况，但其非侵入性评估在实际应用中对用户不够友好。作者研究了血压与光电容积脉搏波描记法（PPG）波形之间的相关性，目的是确定接触压力刺激（PS）的最佳范围，以便在其谐波参数中产生可靠的传递函数。
对健康志愿者（n = 45）同时进行非侵入性测量手指PPG和桡动脉BP信号。对手指施加0 - 200 mmHg的PS，并记录1分钟的数据序列。在频域分析中，对计算出的BP与PPG波形之间的幅度比或前五个谐波进行线性回归。
在60 mmHg - PS组中，幅度比的BP - PPG回归最高，通过Bland - Altman分析验证它们之间的一致性也是最好的。
在本研究中，进行频域分析以研究BP与PPG波形之间的相关性。不同压力诱导的血管舒张反应是应用不同PS获得不同BP - PPG波形相关性的基础。非侵入性得出的PPG参数可能有助于提供一种更简便的方法来获取桡动脉BP波形，从而拓宽BP波形分析的应用。
