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中耳胆固醇肉芽肿的超微结构:一项电子显微镜研究。

The ultrastructure of cholesterol granuloma of the middle ear: an electron microscope study.

作者信息

Friedmann I, Graham M D

出版信息

J Laryngol Otol. 1979 May;93(5):433-42. doi: 10.1017/s0022215100087272.

DOI:10.1017/s0022215100087272
PMID:220348
Abstract

The ultrastructure of giant cells in cholesterol granuloma is described, with particular reference to their role in the absorption of cholesterol needles. Cholesterol is a highly resistant substance in its crystalline form and it is confirmed that the giant cells are endowed with endoplasmic structures and organelles and are partly crowded with lysosomes, as evidence of the active role of the giant cells in the absorption and removal of cholesterol formed in the granuloma from blood, mucus or necrotic material.

摘要

本文描述了胆固醇肉芽肿中巨细胞的超微结构,特别提及了它们在吸收胆固醇结晶方面的作用。胆固醇以结晶形式存在时是一种高度抗分解的物质,现已证实巨细胞具有内质结构和细胞器,并且部分区域充满了溶酶体,这证明了巨细胞在从血液、黏液或坏死物质中吸收和清除肉芽肿中形成的胆固醇过程中发挥着积极作用。

相似文献

1
The ultrastructure of cholesterol granuloma of the middle ear: an electron microscope study.中耳胆固醇肉芽肿的超微结构:一项电子显微镜研究。
J Laryngol Otol. 1979 May;93(5):433-42. doi: 10.1017/s0022215100087272.
2
The ultrastructure of cholesterol granuloma of the middle ear: an electron microscope study. The Journal of Laryngology and Otology, 1979; Vol. 93, pp. 433-442.
J Laryngol Otol. 2002 Nov;116(11):877-81. doi: 10.1258/00222150260369372.
3
[On the importance of cholesterol granuloma (author's transl)].[论胆固醇肉芽肿的重要性(作者译)]
Laryngol Rhinol Otol (Stuttg). 1978 Dec;57(12):1099-109.
4
Resident's page. Pathologic quiz case 2. Cholesterol granuloma.住院医师专页。病理病例问答 2。胆固醇肉芽肿。
Arch Otolaryngol. 1979 Mar;105(3):164-5, 167.
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Electron microscopic study of peripheral giant-cell reparative granuloma.外周巨细胞修复性肉芽肿的电子显微镜研究
Oral Surg Oral Med Oral Pathol. 1977 Jan;43(1):82-96. doi: 10.1016/0030-4220(77)90354-1.
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An ultrastructural study of nuclear and centriolar configurations in multinucleated giant cells.多核巨细胞核与中心粒结构的超微结构研究。
Lab Invest. 1976 Feb;34(2):109-14.
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Pathologic quiz case 2. Cholesterol granuloma.病理病例问答2. 胆固醇肉芽肿。
Arch Otolaryngol Head Neck Surg. 1986 Jun;112(6):674-7.
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[Cholesterol granuloma].
Nihon Jibiinkoka Gakkai Kaiho. 1968 Jun;71(6):877-86.
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Cholesterol granuloma of the middle ear invading the cochlea.中耳胆固醇肉芽肿侵犯耳蜗。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Apr;129(2):104-7. doi: 10.1016/j.anorl.2011.10.009. Epub 2012 Mar 16.
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[Cholesterol granuloma in chronic suppurative otitis media].[慢性化脓性中耳炎中的胆固醇肉芽肿]
Vestn Otorinolaringol. 1984 Jul-Aug(4):27-31.

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Familial hypercholesterolemia with bilateral cholesterol granuloma: A case series.家族性高胆固醇血症伴双侧胆固醇肉芽肿:病例系列
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