Friedmann I, Graham M D
J Laryngol Otol. 1979 May;93(5):433-42. doi: 10.1017/s0022215100087272.
The ultrastructure of giant cells in cholesterol granuloma is described, with particular reference to their role in the absorption of cholesterol needles. Cholesterol is a highly resistant substance in its crystalline form and it is confirmed that the giant cells are endowed with endoplasmic structures and organelles and are partly crowded with lysosomes, as evidence of the active role of the giant cells in the absorption and removal of cholesterol formed in the granuloma from blood, mucus or necrotic material.
本文描述了胆固醇肉芽肿中巨细胞的超微结构,特别提及了它们在吸收胆固醇结晶方面的作用。胆固醇以结晶形式存在时是一种高度抗分解的物质,现已证实巨细胞具有内质结构和细胞器,并且部分区域充满了溶酶体,这证明了巨细胞在从血液、黏液或坏死物质中吸收和清除肉芽肿中形成的胆固醇过程中发挥着积极作用。