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越南儿童盲症的患病率及病因。

Prevalence and causes of blindness in children in Vietnam.

机构信息

International Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.

出版信息

Ophthalmology. 2012 Feb;119(2):355-61. doi: 10.1016/j.ophtha.2011.07.037. Epub 2011 Oct 27.

Abstract

OBJECTIVE

To estimate the prevalence of blindness in children in Vietnam and to assess the major causes.

DESIGN

A population-based study sampled children from 16 provinces across Vietnam. The second study examined children attending all blind schools in Vietnam.

PARTICIPANTS

In 16 provinces, 28 800 children aged 0-15 were sampled. In 28 blind schools, 569 children aged 0-15 were examined.

INTERVENTION

In children not seeing well according to the parents, presenting visual acuity (PVA) was assessed. If PVA was <3/60 in one or both eyes, the child was examined by an ophthalmologist. All children in blind schools were examined by a pediatric ophthalmologist.

MAIN OUTCOME MEASURES

Blindness was defined as PVA <3/60 in the better eye. Causes of visual loss were classified using the World Health Organization classification.

RESULTS

In the population-based study, 22 children had a PVA <3/60 in the better eye, a prevalence of 7.6/10 000 children (95% confidence interval [CI], 4.9-11.8/10 000). Fourteen children had a pinhole visual acuity <3/60 in the better eye, a prevalence of 4.9/10 000 (95% CI, 2.8-8.4/10 000). An estimated 16 400 (95% CI, 10 500-25 300), children were blind from all causes, with 36.4% from uncorrected refractive errors. In the blind schools, 411 children had a PVA <3/60 in the better eye and 55.5% were male. Conditions of the retina (24.6%) and cornea (24.0%) predominated. Retinopathy of prematurity (ROP) caused blindness in 32.6% of children younger than 10 years, but in only 6% of older children. The converse was true for corneal scarring and phthisis (14.0% and 27.3%, respectively). All other causes were similar between age groups (53.5% and 66.7%, respectively). More than half of all causes were avoidable.

CONCLUSIONS

Vietnam is developing very rapidly, and this is impacting health indices. The mortality rate of those younger than 5 years declined from 65/100 live births in 1980 to 14/100 in 2008. The findings of this study show these changes, because the childhood blindness prevalence was relatively low, and the causes show improved control of measles and vitamin A deficiency, as well as increased services for premature babies. Eye care services for children should now focus on refractive errors, cataract, and control of ROP.

摘要

目的

估计越南儿童盲症的患病率,并评估主要病因。

设计

一项基于人群的研究在越南 16 个省抽取了儿童作为样本。第二项研究调查了越南所有盲人学校的学生。

参与者

在 16 个省,共抽取了 28800 名 0-15 岁的儿童。在 28 所盲人学校中,有 569 名 0-15 岁的儿童接受了检查。

干预措施

对于父母报告视力不佳的儿童,评估其视力(PVA)。如果双眼中一眼或两眼的 PVA<3/60,则由眼科医生进行检查。所有盲人学校的儿童均由儿科眼科医生检查。

主要观察指标

盲症定义为较好眼的 PVA<3/60。使用世界卫生组织的分类方法对视力丧失的病因进行分类。

结果

在基于人群的研究中,22 名儿童的较好眼 PVA<3/60,患病率为 7.6/10000 名儿童(95%置信区间[CI],4.9-11.8/10000)。14 名儿童的较好眼针孔视力<3/60,患病率为 4.9/10000(95%CI,2.8-8.4/10000)。估计有 16400 名(95%CI,10500-25300)儿童患有各种病因导致的盲症,其中 36.4%由未矫正的屈光不正引起。在盲人学校,411 名儿童的较好眼 PVA<3/60,其中 55.5%为男性。视网膜(24.6%)和角膜(24.0%)疾病最为常见。早产儿视网膜病变(ROP)导致 10 岁以下儿童失明的比例为 32.6%,而年龄较大的儿童则为 6%。角膜混浊和眼球萎缩(分别为 14.0%和 27.3%)的情况则相反。两组年龄组的其他病因相似(分别为 53.5%和 66.7%)。超过一半的病因是可以预防的。

结论

越南发展迅速,这对健康指标产生了影响。5 岁以下儿童的死亡率从 1980 年的每 100 例活产儿 65 例降至 2008 年的 14 例。本研究的结果表明了这些变化,因为儿童盲症的患病率相对较低,病因表明麻疹和维生素 A 缺乏症的控制有所改善,早产儿的治疗服务也有所增加。儿童眼保健服务现在应重点关注屈光不正、白内障和 ROP 的控制。

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