Service of Ecography and Radiology, Rizzoli Orthopaedic Institute, Bologna, Italy.
Ultrasound Med Biol. 2011 Dec;37(12):1977-83. doi: 10.1016/j.ultrasmedbio.2011.09.004. Epub 2011 Oct 27.
Preoperative diagnosis of septic loosening hip prosthesis is often challenging. Culture test on joint samples obtained during revision surgery is the diagnostic gold standard while the role of preoperative hip aspiration is still controversial. The aims of this prospective randomized study were to compare the sensitivity, specificity and accuracy of preoperative ultrasound-guided and fluoroscopic-guided aspiration, and to identify associated laboratory parameters or scintigraphy that could help in predicting septic loosing hip prosthesis. Sixty patients affected by persistent pain after hip prosthesis randomly received fluoroscopic-guided or ultrasound-guided hip aspiration before revision surgery. The results of culture tests of joint fluid presurgically and at surgery were compared. In addition, associated blood inflammatory markers and scintigraphy were evaluated. Ultrasound-guided aspiration showed a better sensitivity (69% vs. 27%), specificity (94% vs. 75%) and accuracy (83% vs. 40%) than fluoroscopic-guided aspiration. The combination of ultrasound-guided aspiration and C-reactive protein represents the best model to predict septic loosening hip prosthesis preoperatively.
术前诊断感染性髋关节假体松动通常具有挑战性。在翻修手术中获取关节样本进行培养试验是诊断的金标准,而术前髋关节抽吸的作用仍存在争议。本前瞻性随机研究的目的是比较超声引导和透视引导抽吸的敏感性、特异性和准确性,并确定有助于预测感染性髋关节假体松动的相关实验室参数或闪烁扫描。60 例髋关节假体置换术后持续性疼痛患者在翻修术前随机接受透视引导或超声引导髋关节抽吸。比较术前和术中关节液培养试验的结果。此外,还评估了相关血液炎症标志物和闪烁扫描。与透视引导抽吸相比,超声引导抽吸具有更好的敏感性(69%比 27%)、特异性(94%比 75%)和准确性(83%比 40%)。超声引导抽吸与 C 反应蛋白的联合使用是预测术前感染性髋关节假体松动的最佳模型。