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Nuss 手术后的硬膜外和阿片类药物镇痛。

Epidural and opioid analgesia following the Nuss procedure.

机构信息

University Department of Anesthesiology and Intensive Therapy, Medical University of Silesia, Zabrze, Poland.

出版信息

Med Sci Monit. 2011 Nov;17(11):PH81-86. doi: 10.12659/msm.882032.

Abstract

BACKGROUND

Parents have the right to decide on behalf of their children and deny consent to regional anaesthesia. The investigators decided to investigate quality of postoperative analgesia in adolescents undergoing epidural and opioid analgesia following the Nuss procedure. material/methods: The study subjects were 61 adolescents aged 11-18 years who underwent pectus excavatum repair with the Nuss procedure. Patients were divided into epidural (n=41) and opioid (n=20) groups, depending on their parents' consent to epidural catheter insertion. Intraoperatively, 0.5% epidural ropivacaine with fentanyl or intermittent intravenous injections of fentanyl were used. Postoperative analgesia was achieved with either epidural infusion of 0.1% ropivacaine with fentanyl, or subcutaneous morphine via an intraoperatively inserted "butterfly" cannula. Additionally, both groups received metamizol and paracetamol. Primary outcome variables were postoperative pain scores (Numeric Rating Scale and Prince Henry Hospital Pain Score). Secondary outcome variables included hemodynamic parameters, additional analgesia and side effects.

RESULTS

Heart rate and blood pressure values in the postoperative period were significantly higher in the opioid group. Pain scores requiring intervention were noted almost exclusively in the opioid group.

CONCLUSIONS

Denial of parental consent to epidural analgesia following the Nuss procedure results in significantly worse control of postoperative pain. Our data may be useful when discussing with parents the available anaesthetic techniques for exceptionally painful procedures.

摘要

背景

父母有权代表孩子做出决定并拒绝同意局部麻醉。研究人员决定调查接受 Nuss 手术后接受硬膜外和阿片类药物镇痛的青少年术后镇痛质量。

材料/方法:本研究对象为 61 名 11-18 岁接受漏斗胸修复术的青少年。根据父母对硬膜外导管插入的同意,将患者分为硬膜外组(n=41)和阿片组(n=20)。术中使用 0.5%罗哌卡因+芬太尼行硬膜外麻醉或间断静脉注射芬太尼。术后镇痛采用 0.1%罗哌卡因+芬太尼硬膜外输注或术中插入的“蝴蝶”导管行皮下吗啡镇痛。此外,两组均给予扑热息痛和对乙酰氨基酚。主要观察变量为术后疼痛评分(数字评分量表和 Prince Henry 医院疼痛评分)。次要观察变量包括血流动力学参数、额外镇痛和副作用。

结果

阿片组术后心动过速和血压值明显升高。需要干预的疼痛评分几乎仅见于阿片组。

结论

拒绝父母同意 Nuss 手术后行硬膜外镇痛会导致术后疼痛控制明显恶化。当与父母讨论特定疼痛手术的可用麻醉技术时,我们的数据可能会很有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8d3/3539505/c1f304678ea4/medscimonit-17-11-PH81-g001.jpg

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