a Central Veterinary Institue , P.O. Box 6007 , Rotterdam , 3002 AA , The Netherlands.
Vet Q. 1979 Jul;1(3):126-33. doi: 10.1080/01652176.1979.9693734.
Summary A field case of mastitis in cows, caused by Mycoplasma agalactiae var. bovis, formed the occasion to conduct an infection experiment. Five lactating heifers were infected in the udder at different times. The cows were slaughtered 2, 5, 7, 9 and 12 days p. i. and the pathological changes were studied. The investigation indicated that the pathological picture differed with time: in the acute stage, the inflammation was characterized by exudation of mostly eosinophils in the alveoli; later on, the mastitis was identified by an interstitial reaction with eosinophils and mononuclear cells, including plasma cells and lymphocytes; in the chronic stage, progressive fibroplasia around ductuli and alveoli, with hypertrophy of alveolar epithelium, was characteristic. The pathological findings are discussed.
牛乳腺炎的田间病例，由牛支原体变种引起，为此进行了感染实验。五只哺乳期奶牛在不同时间于乳房内受到感染。奶牛在感染后第 2、5、7、9 和 12 天被屠宰，研究了病理变化。调查表明，随着时间的推移，病理图像有所不同：在急性阶段，炎症的特征是肺泡中主要有嗜酸性粒细胞渗出；后来，乳腺炎被确定为一种间质反应，其中包括嗜酸性粒细胞和单核细胞，如浆细胞和淋巴细胞；在慢性阶段，围绕小管和肺泡的进行性纤维增生，以及肺泡上皮的肥大是特征。讨论了病理发现。
