Department of BioMechanical Engineering, Faculty of Mechanical, Maritime & Materials Engineering, Delft University of Technology, The Netherlands.
Acta Paediatr. 2012 Mar;101(3):e97-104. doi: 10.1111/j.1651-2227.2011.02506.x. Epub 2011 Nov 22.
To quantify manual fraction of inspired oxygen (FiO(2)) adjustments performed by caregivers in extremely low birth weight (ELBW; ≤1000 g) infants, in relation to oxygen saturation (SpO(2)) and bedside care.
In a single-centre study, FiO(2) , SpO(2) and alarm limits of ELBW infants were collected for 3 days continuously, while caregivers were filmed. A descriptive analysis, focused on manual FiO(2) adjustments, was performed.
Twelve ELWB infants were included. Total recording time was 726 h. FiO(2) was increased 851 times and decreased 1309 times; median (range) step size was 5% (1% to 65%) and -3% (-1% to -65%), respectively. Wide variation of FiO(2) adjustments for equal levels of SpO(2) was observed in all included infants. One hundred and twenty-six of 136 FiO(2) adjustments with a step size ≥15% and 111 of 171 desaturations <70% were associated with medical or nursing procedures. When FiO(2) was >21%, alarm limits for SpO(2) were set according to protocol (88-94%) in 64% of the time. Within these periods, SpO(2) was >94% for 30% and <88% for 16% of the time.
Manual FiO(2) adjustments varied widely in frequency and step size. Deep desaturations and large FiO(2) adjustments were associated with medical or nursing procedures. When large adjustments are really necessary, it will be challenging to implement them in an automatic adjustment device.
定量分析极低出生体重（ELBW；≤1000g）婴儿的护理人员在调整吸入氧分数（FiO₂）时，与氧饱和度（SpO₂）和床边护理的关系。
在单中心研究中，连续 3 天连续收集 ELBW 婴儿的 FiO₂、SpO₂和报警限，同时对护理人员进行录像。进行描述性分析，重点关注手动 FiO₂调整。
共纳入 12 例 ELBW 婴儿。总记录时间为 726 小时。FiO₂增加 851 次，减少 1309 次；中位数（范围）步长分别为 5%（1%至 65%）和-3%（-1%至-65%）。所有纳入婴儿的 SpO₂相等水平的 FiO₂调整差异较大。136 次 FiO₂调整中有 126 次步长≥15%，171 次脱氧饱和度<70%与医疗或护理程序有关。当 FiO₂>21%时，根据协议（88-94%）设置 SpO₂的报警限时间为 64%。在这些期间，SpO₂>94%的时间为 30%，<88%的时间为 16%。
手动 FiO₂调整的频率和步长差异很大。深度脱氧和大 FiO₂调整与医疗或护理程序有关。当确实需要大的调整时，在自动调整装置中实施它们将具有挑战性。
