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电化学疗法治疗溃疡性基底细胞癌的疗效

Efficacy of electrochemotherapy in ulcerated basal cell carcinoma.

作者信息

Richetta A G, Curatolo P, D'Epiro S, Mancini M, Mattozzi C, Giancristoforo S, Rotunno R, Calvieri S

机构信息

Department of Dermatology, Umberto I Hospital, University Sapienza, Rome, Italy.

出版信息

Clin Ter. 2011;162(5):443-5.

Abstract

Basal cell carcinoma is the most common cutaneous malignant tumor, accounting for up to 80% of non melanoma skin cancers. Surgery, radiotherapy and chemotherapy have been for long time the main options for its treatment. Electrochemotherapy (ECT) is a novel local treatment successfully used in primary skin tumors. We report a case of a man affected by ulcerated basal cell carcinoma treated with ECT. In our case ECT was successful in the management of extensive basal cell carcinoma in clinical conditions whereas other approaches, would have been dangerous and inappropriate. To our knowledge, ECT must be considered as an alternative of traditional techniques when they are contraindicated in relation to the appearance of the lesions or the patient medical history.

摘要

基底细胞癌是最常见的皮肤恶性肿瘤,占非黑色素瘤皮肤癌的比例高达80%。长期以来,手术、放疗和化疗一直是其主要治疗手段。电化学疗法(ECT)是一种成功应用于原发性皮肤肿瘤的新型局部治疗方法。我们报告一例患有溃疡性基底细胞癌的男性患者接受ECT治疗的病例。在我们的病例中,ECT成功地治疗了临床条件下的广泛性基底细胞癌,而其他方法可能会很危险且不合适。据我们所知,当传统技术因病变外观或患者病史而禁忌时,ECT可被视为一种替代方法。

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