Mornex René
l'Académie nationale de médecine.
Bull Acad Natl Med. 2010 Dec;194(9):1669-74.
With the publication of l"Introduction à l'étude de la médecine expérimentale (Introduction to the Study of Experimental Medicine) in 1865, Claude Bernard opened up a new concept in experimental methodology. By stressing the essential link between clinical observation, exploration of the "internal medium", and animal studies, he established the founding principles of clinical research.
随着1865年《实验医学研究导论》的出版,克洛德·贝尔纳开创了实验方法论的新概念。通过强调临床观察、“内环境”探索与动物研究之间的本质联系,他确立了临床研究的基本原则。