Accordino Robert E, Langs-Barlow Allison, Phelps Robert G, Hammond Blair, Mercer Stephen E
Department of Medical Education, Mount Sinai School of Medicine, New York, NY 10029, USA.
Pediatr Dermatol. 2012 Mar-Apr;29(2):220-2. doi: 10.1111/j.1525-1470.2011.01574.x. Epub 2011 Nov 2.
Melanonychia is a black, tan, or brown streak within the nail plate subsequent to activation of melanocytes in the nail matrix. We present a case of a Haitian girl who presented with transverse melanonychia involving all 10 fingernails in the setting of hyperthyroidism and acute liver injury. Melanonychia has been described only one time in the literature in the setting of hyperthyroidism though this patient also underwent radium treatment which could have led to nail changes.
甲下黑素沉着是指在甲母质中黑素细胞激活后,甲床内出现黑色、棕褐色或褐色条纹。我们报告一例海地女孩,她在甲状腺功能亢进和急性肝损伤的情况下出现累及所有10个手指甲的横向甲下黑素沉着。尽管该患者还接受过镭治疗,这可能导致指甲改变,但在文献中仅一次描述了甲状腺功能亢进情况下的甲下黑素沉着。