肝硬化分类：肝静脉压力梯度测量的临床应用。
Classification of cirrhosis: the clinical use of HVPG measurements.
机构信息
Department of Gastoenterology and Hepatology, Hospital Ramón y Cajal, Madrid, Spain.
出版信息
Dis Markers. 2011;31(3):121-8. doi: 10.3233/DMA-2011-0834.
Abstract
The modern paradigm considers cirrhosis as a dynamic and potentially reversible disease. It consists of two different entities, compensated and decompensated cirrhosis, each with a distinct prognosis and different predictors of survival. The development of portal hypertension is a hallmark in the history of cirrhosis, and its progression parallels that of the disease. In consequence, portal pressure measurement by means of HVPG allows stratifying cirrhosis in stages with defined outcomes, prognosis, and management strategies.
摘要
现代观点认为肝硬化是一种动态的、具有潜在可逆性的疾病。它由两个不同的实体组成，代偿性和失代偿性肝硬化，每个实体都有不同的预后和不同的生存预测因素。门静脉高压的发展是肝硬化病程中的一个标志，其进展与疾病的进展平行。因此，通过测量 HVPG 可以将肝硬化分为不同阶段，每个阶段都有明确的结局、预后和管理策略。
相似文献
1
Classification of cirrhosis: the clinical use of HVPG measurements.肝硬化分类：肝静脉压力梯度测量的临床应用。
Dis Markers. 2011;31(3):121-8. doi: 10.3233/DMA-2011-0834.
2
New concepts on the clinical course and stratification of compensated and decompensated cirrhosis.代偿期和失代偿期肝硬化的临床病程和分层的新概念。
Hepatol Int. 2018 Feb;12(Suppl 1):34-43. doi: 10.1007/s12072-017-9808-z. Epub 2017 Jul 5.
3
Diagnostic and prognostic markers in liver cirrhosis.肝硬化的诊断和预后标志物
Dis Markers. 2011;31(3):119-20. doi: 10.3233/DMA-2011-0833.
4
Prognostic indicators of survival in patients with compensated and decompensated cirrhosis.代偿期和失代偿期肝硬化患者的生存预后指标。
Liver Int. 2012 Oct;32(9):1407-14. doi: 10.1111/j.1478-3231.2012.02830.x. Epub 2012 Jun 11.
5
Prognostic assessment in patients with hepatic encephalopathy.肝性脑病患者的预后评估。
Dis Markers. 2011;31(3):171-9. doi: 10.3233/DMA-2011-0840.
6
Prognostic markers in patients with cirrhosis and portal hypertension who have not bled.未出血的肝硬化和门静脉高压患者的预后标志物。
Dis Markers. 2011;31(3):147-54. doi: 10.3233/DMA-2011-0837.
7
Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.肝静脉压力梯度可预测代偿期肝硬化患者的临床失代偿情况。
Gastroenterology. 2007 Aug;133(2):481-8. doi: 10.1053/j.gastro.2007.05.024. Epub 2007 May 21.
8
Prognostic markers in patients with ascites and hepatorenal syndrome.腹水和肝肾综合征患者的预后标志物
Dis Markers. 2011;31(3):139-46. doi: 10.3233/DMA-2011-0836.
9
The portal hypertension syndrome: etiology, classification, relevance, and animal models.门静脉高压综合征：病因、分类、相关性及动物模型。
Hepatol Int. 2018 Feb;12(Suppl 1):1-10. doi: 10.1007/s12072-017-9827-9. Epub 2017 Oct 24.
10
Clinical significance of measuring hepatic venous pressure gradient on transjugular liver biopsy for patients with pre-cirrhotic bridging fibrosis liver disease.经颈静脉肝活检时测量肝静脉压力梯度对肝硬化前桥接纤维化肝病患者的临床意义。
Clin Imaging. 2023 Apr;96:44-48. doi: 10.1016/j.clinimag.2023.02.004. Epub 2023 Feb 10.
引用本文的文献
1
Standard technique in Japan for measuring hepatic venous pressure gradient.日本测量肝静脉压力梯度的标准技术。
J Gastroenterol. 2025 Jan;60(1):24-31. doi: 10.1007/s00535-024-02182-z. Epub 2024 Dec 9.
2
Esophageal Varices as an Independent Predictor of Fatal Outcomes after Balloon-Occluded Retrograde Transvenous Obliteration in Patients with Hepatic Encephalopathy.食管静脉曲张作为肝性脑病患者经皮球囊闭塞逆行静脉栓塞术后致命结局的独立预测因素。
Dig Dis. 2024;42(6):583-592. doi: 10.1159/000541660. Epub 2024 Sep 30.
3
History of liver surgery.肝脏手术史。
Clin Liver Dis (Hoboken). 2024 Jun 25;23(1):e0237. doi: 10.1097/CLD.0000000000000237. eCollection 2024 Jan-Jun.
4
Prognostic Indicators of Overall Survival in Hepatocellular Carcinoma Patients Undergoing Liver Resection.接受肝切除的肝细胞癌患者总生存的预后指标
Cancers (Basel). 2024 Apr 7;16(7):1427. doi: 10.3390/cancers16071427.
5
Keep beta-blocking and carry on!持续使用β受体阻滞剂并继续治疗！
Clin Liver Dis (Hoboken). 2024 Jan 31;23(1):e0114. doi: 10.1097/CLD.0000000000000114. eCollection 2024 Jan-Jun.
6
Clinical Characteristics, Etiology, and Prognostic Scores in Patients with Acute Decompensated Liver Cirrhosis.急性失代偿期肝硬化患者的临床特征、病因及预后评分
J Clin Med. 2023 Sep 4;12(17):5756. doi: 10.3390/jcm12175756.
7
The future of hepatology.肝脏病学的未来。
Hepatology. 2023 Aug 1;78(2):637-648. doi: 10.1097/HEP.0000000000000389. Epub 2023 Apr 5.
8
Percutaneous transhepatic obliteration for life-threatening bleeding after endoscopic variceal ligation in a patient with severe esophagogastric varices.经皮经肝闭塞术治疗严重食管胃静脉曲张患者内镜下静脉曲张结扎术后危及生命的出血
Radiol Case Rep. 2022 Nov 30;18(2):624-630. doi: 10.1016/j.radcr.2022.10.105. eCollection 2023 Feb.
9
Verification of thrombus formation just after endoscopic injection sclerotherapy with ligation for esophagogastric varices by venous phase of left gastric arteriography.通过胃左动脉造影静脉期验证内镜下注射硬化剂联合结扎术治疗食管胃静脉曲张后血栓形成情况。
Radiol Case Rep. 2022 Aug 27;17(11):4069-4074. doi: 10.1016/j.radcr.2022.07.098. eCollection 2022 Nov.
10
What Makes Cirrhosis Irreversible?-Consideration on Structural Changes.是什么导致肝硬化不可逆转？——关于结构变化的思考
Front Med (Lausanne). 2022 Apr 27;9:876293. doi: 10.3389/fmed.2022.876293. eCollection 2022.
Zotero 插件