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1
Genetic evidence for preferential strand transfer during meiotic recombination in yeast.酵母减数分裂重组过程中优先链转移的遗传证据。
Genetics. 1990 Aug;125(4):753-61. doi: 10.1093/genetics/125.4.753.
2
Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.酿酒酵母减数分裂重组过程中形成的特定碱基对错配的修复。
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3
Rapid kinetics of mismatch repair of heteroduplex DNA that is formed during recombination in yeast.酵母重组过程中形成的异源双链DNA错配修复的快速动力学。
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4
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5
Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.遗传证据表明，酿酒酵母HIS4基因座处的减数分裂重组热点并不代表对称处理双链断裂的位点。
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Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination.酿酒酵母中未修复的异源双链DNA在不依赖RAD1和RAD52的重组中减少。
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Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae.酿酒酵母减数分裂重组过程中形成的切除修复片段的测量。
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Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae.酿酒酵母减数分裂重组过程中异源双链体的物理检测。
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10
Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae.酿酒酵母减数分裂重组过程中形成的DNA错配的转换型和修复型修复
Genetics. 1998 Aug;149(4):1693-705. doi: 10.1093/genetics/149.4.1693.

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2
Fragile site instability in Saccharomyces cerevisiae causes loss of heterozygosity by mitotic crossovers and break-induced replication.酿酒酵母中的脆性位点不稳定性通过有丝分裂交叉和断裂诱导复制导致杂合性丢失。
PLoS Genet. 2013;9(9):e1003817. doi: 10.1371/journal.pgen.1003817. Epub 2013 Sep 19.
3
Physical analyses of E. coli heteroduplex recombination products in vivo: on the prevalence of 5' and 3' patches.大肠杆菌体内异源双链重组产物的物理分析：关于5'和3'片段的普遍性
PLoS One. 2007 Nov 28;2(11):e1242. doi: 10.1371/journal.pone.0001242.
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Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae.与酿酒酵母减数分裂重组起始相关的异源双链体形成模式。
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Triplet repeats form secondary structures that escape DNA repair in yeast.三核苷酸重复序列形成的二级结构可逃避酵母中的DNA修复。
Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1504-9. doi: 10.1073/pnas.96.4.1504.
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Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae.酿酒酵母减数分裂重组过程中形成的DNA错配的转换型和修复型修复
Genetics. 1998 Aug;149(4):1693-705. doi: 10.1093/genetics/149.4.1693.
7
Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.遗传证据表明，酿酒酵母HIS4基因座处的减数分裂重组热点并不代表对称处理双链断裂的位点。
Genetics. 1993 May;134(1):5-19. doi: 10.1093/genetics/134.1.5.
8
Meiotic mismatch repair quantified on the basis of segregation patterns in Schizosaccharomyces pombe.基于粟酒裂殖酵母中的分离模式对减数分裂错配修复进行量化。
Genetics. 1993 Apr;133(4):815-24. doi: 10.1093/genetics/133.4.815.
9
Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase.酿酒酵母减数分裂中分子事件的时间安排：稳定的异源双链DNA在减数分裂前期后期形成。
Mol Cell Biol. 1993 Jan;13(1):373-82. doi: 10.1128/mcb.13.1.373-382.1993.
10
Polarity of meiotic gene conversion in fungi: contrasting views.真菌减数分裂基因转换的极性：不同观点
Experientia. 1994 Mar 15;50(3):242-52. doi: 10.1007/BF01924007.

本文引用的文献

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The double-strand-break repair model for recombination.用于重组的双链断裂修复模型。
Cell. 1983 May;33(1):25-35. doi: 10.1016/0092-8674(83)90331-8.
2
Homologous pairing and strand exchange in genetic recombination.遗传重组中的同源配对与链交换。
Annu Rev Genet. 1982;16:405-37. doi: 10.1146/annurev.ge.16.120182.002201.
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Meiotic gene conversion in yeast tetrads and the theory of recombination.酵母四分体中的减数分裂基因转换与重组理论。
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Postmeiotic segregation in Saccharomyces.酿酒酵母中的减数分裂后分离
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Evidence for meiotic recombination in Ascobolus involving only one member of a tetrad.关于粪壳菌减数分裂重组仅涉及四分体中一个成员的证据。
Genetics. 1971 Jul;68(3):401-13. doi: 10.1093/genetics/68.3.401.
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Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2.酿酒酵母中的减数分裂基因转换突变体。I. pms1-1和pms1-2的分离与鉴定。
Genetics. 1985 Aug;110(4):609-46. doi: 10.1093/genetics/110.4.609.
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Mismatch-specific post-meiotic segregation frequency in yeast suggests a heteroduplex recombination intermediate.酵母中错配特异性减数分裂后分离频率表明存在异源双链体重组中间体。
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Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region.
Mol Cell Biol. 1988 Jul;8(7):2955-63. doi: 10.1128/mcb.8.7.2955-2963.1988.
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DNA double-chain breaks in recombination of phage lambda and of yeast.噬菌体λ和酵母重组过程中的DNA双链断裂
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10
Expansions and contractions of the genetic map relative to the physical map of yeast chromosome III.酵母第三号染色体遗传图谱相对于物理图谱的扩展与收缩。
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酵母减数分裂重组过程中优先链转移的遗传证据。

Genetic evidence for preferential strand transfer during meiotic recombination in yeast.

作者信息

Nag D K, Petes T D

机构信息

Department of Biology, University of North Carolina, Chapel Hill 27599-3280.

出版信息

Genetics. 1990 Aug;125(4):753-61. doi: 10.1093/genetics/125.4.753.

DOI:10.1093/genetics/125.4.753
PMID:2204581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1204101/
Abstract

During meiotic recombination in the yeast Saccharomyces cerevisiae, heteroduplexes are formed as an intermediate in the exchange process. In the formation of an asymmetric heteroduplex, one chromosome acts as a donor of a single DNA strand and the other acts as a recipient. We present genetic evidence that the nontranscribed strand is donated more frequently than the transcribed strand in spores that have an unrepaired mismatch at the HIS4 locus.

摘要

在酿酒酵母的减数分裂重组过程中，异源双链体作为交换过程中的中间体形成。在不对称异源双链体的形成中，一条染色体作为单链DNA的供体，另一条作为受体。我们提供了遗传学证据，即在HIS4位点存在未修复错配的孢子中，非转录链比转录链更频繁地被捐赠。