Pădure Livia, Ignat Ileana Sînziana, Eşanu Irina, Hurjui J
Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Medicină.
Rev Med Chir Soc Med Nat Iasi. 2011 Jul-Sep;115(3):889-93.
The concept of normohemodynamics is based on the fact that the main function of the cardiovascular system is the transport of oxygen. The cardiovascular system is adapting to a new hemodynamic status with every heartbeat. Only one class, called the normohemodynamic state, containing a simultaneous normotension and normodynamic flow, can serve as therapeutic goal. Metabolic syndrome includes a constellation of clinical and biological features that confer an increased cardiovascular risk. Clutter hemodynamic modulators in metabolic syndrome and assessment of hemodynamic status both overall and by its components, open new perspectives in the management of patients with hypertension and metabolic syndrome.
In the current study were included 32 patients meeting the criteria for metabolic syndrome and hypertension and 32 controls. Patients were monitored and assessed for the global hemodynamic status and for the modulators of hemodynamics, intravascular volume, vasoactivity and inotropy, respectively.
There are no significant differences in the global hemodynamic status between the study group and the control group; in the study group there is a clear weathering of hemodynamic modulators. The improvement of these factors opens a new perspective in the global cardiovascular assessment and therapeutic directions.
正常血流动力学的概念基于心血管系统的主要功能是输送氧气这一事实。心血管系统每一次心跳都会适应一种新的血流动力学状态。只有一种状态,即同时具备正常血压和正常动力血流的正常血流动力学状态,可作为治疗目标。代谢综合征包括一系列会增加心血管风险的临床和生物学特征。代谢综合征中的紊乱血流动力学调节因子以及对整体和各组成部分血流动力学状态的评估,为高血压和代谢综合征患者的管理开辟了新的视角。
本研究纳入了32例符合代谢综合征和高血压标准的患者以及32例对照。分别对患者的整体血流动力学状态以及血流动力学调节因子、血管内容量、血管活性和心肌收缩力进行监测和评估。
研究组与对照组在整体血流动力学状态方面无显著差异;研究组中血流动力学调节因子存在明显损耗。这些因素的改善为整体心血管评估和治疗方向开辟了新的视角。