Coleman Technologies, Inc., 5131 West Chester Pike, Newtown Square, Pennsylvania 19073, USA.
Opt Lett. 2011 Nov 1;36(21):4206-8. doi: 10.1364/OL.36.004206.
Optical aberrations deteriorate the performance of microscopes. Adaptive optics can be used to improve imaging performance via wavefront shaping. Here, we demonstrate a pupil-segmentation based adaptive optical approach with full-pupil illumination. When implemented in a two-photon fluorescence microscope, it recovers diffraction-limited performance and improves imaging signal and resolution.
像差会降低显微镜的性能。自适应光学可以通过波前整形来提高成像性能。在这里，我们展示了一种基于瞳孔分割的自适应光学方法，该方法采用全瞳孔照明。当应用于双光子荧光显微镜时，它可以恢复衍射极限性能，并提高成像信号和分辨率。
