Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MP 702, Seattle, WA 98109, USA; University of Washington, USA.
J Health Psychol. 2000 Jan;5(1):109-15. doi: 10.1177/135910530000500103.
Behavioral research has an important role in increasing and maintaining participation in disease prevention trials, both in interventions and in follow-up visits. We conducted a randomized experiment among participants in the lung cancer chemoprevention trial, CARET (Carotene and Retinol Efficacy Trial) to test the effects of providing two incentives on retention. The items used for this study were a Certificate of Appreciation and one of two lapel pins, provided in a 2 2 design. Providing incentives, whether alone or in combination, had no statistically significant effect on retention by the two-year follow-up point. The successful implementation of this randomized incentive study has two implications for future research: (1) study of behavioral interventions and issues is feasible in the context of large controlled trials of disease end-points; and (2) such study is necessary to determine whether selected incentives can increase retention.
行为研究在增加和维持疾病预防试验的参与度方面具有重要作用，无论是干预措施还是随访访问。我们在肺癌化学预防试验 CARET（胡萝卜素和视黄醇功效试验）的参与者中进行了一项随机实验，以测试提供两种激励措施对保留率的影响。这项研究使用的项目是一份感谢证书和两个领针中的一个，以 2 2 的设计提供。通过两年的随访点，激励措施无论是单独使用还是组合使用，对保留率都没有统计学上的显著影响。这项随机激励研究的成功实施对未来的研究有两个启示：（1）在大型疾病终点对照试验的背景下，进行行为干预和问题的研究是可行的；（2）这种研究是必要的，以确定是否可以选择激励措施来提高保留率。
