Nolte S, Hanjani P
Department of Obstetrics and Gynecology, Temple University Health Science Center, Philadelphia, PA 19104.
Semin Oncol Nurs. 1990 Aug;6(3):181-9. doi: 10.1016/0749-2081(90)90002-m.
The incidence of CIN, VIN, and VAIN has increased dramatically in recent years due to a true increase in disease incidence as well as improved screening methods. Associated high-risk factors in the development of intraepithelial neoplasia are known, and effective treatment modalities are available. With the use of diagnostic techniques, patient education, and selection and utilization of appropriate therapies, intraepithelial neoplasia of the lower genital tract remains a disease that should not affect long-term morbidity, social status, or mortality of female patients.
近年来，由于疾病发病率的实际上升以及筛查方法的改进，宫颈上皮内瘤变（CIN）、外阴上皮内瘤变（VIN）和阴道上皮内瘤变（VAIN）的发病率急剧上升。上皮内瘤变发生过程中的相关高危因素已为人所知，且有有效的治疗方式。通过运用诊断技术、开展患者教育以及选择和使用合适的治疗方法，下生殖道上皮内瘤变仍是一种不应影响女性患者长期发病率、社会地位或死亡率的疾病。
