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[女童生殖器恶性肿瘤]

[Malignant tumors of the genitalia in girls].

作者信息

Bokhman Ia V, Nechaeva I D, Maksimov S Ia, Kutusheva G F, Kolygin B A

出版信息

Vopr Onkol. 1986;32(1):74-80.

PMID:3511609
Abstract

A review of the literature and analysis of 40 cases of genital malignancies girls are presented. 31 patients had ovarian tumor, 2--cervical, 4--vaginal and 3--tumor of the vulva. Most embryonal rhabdomyosarcoma of the vagina or the vulva occurred in patients under 4 whereas ovarian neoplasms (mostly germ and sex cord tumors) were observed at prepubertal and pubertal age. Early dissemination and unfavorable prognosis were typical of rhabdomyosarcoma of the vagina and vulva. Stage I dysgerminoma and granulosa cell tumor usually make the case for sparing surgery whereas stage II and III malignancies--for a radical one, irrespective of histological pattern. Prognosis is better when surgery is supplemented with individually-tailored chemotherapy.

摘要

本文对40例女童生殖器恶性肿瘤进行了文献综述和分析。31例患者患有卵巢肿瘤,2例为宫颈癌,4例为阴道癌,3例为外阴癌。大多数阴道或外阴胚胎性横纹肌肉瘤发生在4岁以下的患者中,而卵巢肿瘤(主要是生殖细胞和性索肿瘤)则在青春期前和青春期出现。阴道和外阴横纹肌肉瘤的典型特征是早期扩散和预后不良。Ⅰ期无性细胞瘤和颗粒细胞瘤通常适合保留手术,而Ⅱ期和Ⅲ期恶性肿瘤则适合根治性手术,无论组织学类型如何。手术辅以个体化化疗时预后较好。

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