Schulz T F, Larcher C, Dierich M P
Institute for Cancer Research, London.
Z Hautkr. 1990 Jul;65(7):619-22, 625-6, 629-32.
Since its discovery in 1983, a lot of knowledge about the human immunodeficiency virus (HIV) has been accumulated. Our paper gives a brief survey on what is known at present about the structure, molecular biology, and the cell tropism of this virus. We discuss its relationship to other lentiviruses as well as its possible origin; in addition, we refer to the immune response to HIV and its interactions with the infected host. We also briefly summarize the difficulties encountered in the attempts to produce a vaccine against HIV and highlight some promising approaches in the development of such a vaccine.
自1983年人类免疫缺陷病毒（HIV）被发现以来，人们已积累了大量关于它的知识。我们的论文简要综述了目前已知的关于该病毒的结构、分子生物学及细胞嗜性的信息。我们讨论了它与其他慢病毒的关系及其可能的起源；此外，我们还提及了针对HIV的免疫反应及其与受感染宿主的相互作用。我们还简要总结了在研发抗HIV疫苗的尝试中遇到的困难，并强调了开发此类疫苗的一些有前景的方法。
