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[HIV感染的病因发病机制]

[Etiopathogenesis of HIV infection].

作者信息

Pérez Alvarez L

出版信息

Arch Neurobiol (Madr). 1989;52 Suppl 1:17-22.

PMID:2700293
Abstract

The knowledge of life's cycle of the acquired immune deficiency syndrome's virus (HIV) its complex genetic structure involving the interaction of positive and negative regulatory gene controlling the growth of the virus, its great genetic variability, the different pathogenic mechanisms, the cell-virus interaction, the different host-cells and the interaction of other pathogens, are all fundamentals facts for a better understanding of the various stages of infection by HIV until ultimate establishment of the Acquired Immune Deficiency Syndrome and also to explain the therapeutic difficulties until now.

摘要

了解获得性免疫缺陷综合征病毒(HIV)的生命周期、其复杂的遗传结构(涉及控制病毒生长的正负调节基因的相互作用)、巨大的遗传变异性、不同的致病机制、细胞与病毒的相互作用、不同的宿主细胞以及其他病原体的相互作用,都是更好地理解HIV感染各个阶段直至最终发展为获得性免疫缺陷综合征的基本事实,也有助于解释迄今为止的治疗困难。

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