Dayan Steven H, Arkins John P, Mathison Clyde C
Chicago Center for Facial Plastic Surgery, Chicago, IL 60611, USA.
J Drugs Dermatol. 2011 Sep;10(9):1007-12.
As the number of soft tissue filler injections increases, the number of adverse events associated with injection may rise. Impending necrosis represents a serious complication that, if not treated correctly and timely, may have grave consequences.
We describe a protocol utilizing hyaluronidase, nitroglycerin paste, aspirin, antacid and a topical oxygen therapy that may be used to treat impending necrosis subsequent to injection with soft tissue fillers.
We have successfully treated nine post-filler injection adverse events involving impending necrosis or necrosis following both hyaluronic acid and calcium hydroxylapatite injections using our protocol.
随着软组织填充剂注射数量的增加，与注射相关的不良事件数量可能会上升。即将发生的坏死是一种严重的并发症，如果没有得到正确及时的治疗，可能会产生严重后果。
我们描述了一种使用透明质酸酶、硝酸甘油糊剂、阿司匹林、抗酸剂和局部氧疗的方案，可用于治疗软组织填充剂注射后即将发生的坏死。
我们使用该方案成功治疗了9例填充剂注射后的不良事件，这些事件涉及透明质酸和羟基磷灰石钙注射后即将发生的坏死或坏死。
