Caranti Alberto, Thomas Radulesco, Facchini Fabio, Campisi Ruggero, Bianchini Chiara, Pelucchi Stefano, Ciorba Andrea, Iannella Gianicola, Maniaci Antonino, Michel Justin, Vicini Claudio
Primus Medical Center (GVM), Gruppo Otorinolaringoiatrico della Romagna, Via Punta di Ferro 2/c, 47122, Forlì, FC, Italy.
Otorhinolaryngology and Audiology Unit, Department of Neurosciences and Rehabilitation, University of Study of Ferrara, via Aldo Moro 8, 44124, Ferrara, FE, Italy.
Aesthetic Plast Surg. 2025 Jan 2. doi: 10.1007/s00266-024-04636-4.
The increasing popularity of cosmetic procedures has led to a rise in both surgical and nonsurgical interventions. Rhinoplasty, particularly nonsurgical rhinoplasty using injectable fillers such as hyaluronic acid (HA), has become highly sought after due to its minimally invasive nature. Despite its benefits, complications can occur, ranging from minor to severe.
This narrative review adheres to PRISMA guidelines and evaluates the complications associated with injectable rhinofillers. A comprehensive search was conducted in PubMed and Embase databases for articles published between January 1, 1990, and September 30, 2023, using specific keywords related to nonsurgical rhinoplasty and its complications. A total of 180 articles were identified, with 80 included in the final review.
Complications from injectable rhinofillers vary widely. Common early-onset issues include asymmetry, injection site reactions, and hypersensitivity. Severe complications like vascular occlusion can lead to tissue ischemia, necrosis, or even blindness. Infection, Tyndall effect, nodules, granulomas, scarring, and biofilms are also documented. The incidence of severe complications is relatively low but requires immediate and effective management to prevent long-term consequences.
Nonsurgical rhinoplasty using fillers, particularly HA, is generally safe with a low risk of severe complications. Awareness and prompt management of potential complications are crucial for practitioners. Preventative measures, precise techniques, and thorough anatomical knowledge can mitigate risks, ensuring better patient outcomes.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
美容手术越来越受欢迎，导致手术和非手术干预的数量都有所增加。隆鼻术，尤其是使用透明质酸（HA）等可注射填充剂的非手术隆鼻术，因其微创性而备受青睐。尽管有其益处，但仍可能发生并发症，范围从轻微到严重。
本叙述性综述遵循PRISMA指南，评估与可注射隆鼻填充剂相关的并发症。在PubMed和Embase数据库中进行了全面检索，以查找1990年1月1日至2023年9月30日期间发表的文章，使用了与非手术隆鼻术及其并发症相关的特定关键词。共识别出180篇文章，其中80篇纳入最终综述。
可注射隆鼻填充剂引起的并发症差异很大。常见的早期问题包括不对称、注射部位反应和超敏反应。血管阻塞等严重并发症可导致组织缺血、坏死，甚至失明。感染、廷德尔效应、结节、肉芽肿、瘢痕形成和生物膜也有记录。严重并发症的发生率相对较低，但需要立即进行有效处理以防止长期后果。
使用填充剂，尤其是HA的非手术隆鼻术总体上是安全的，严重并发症风险较低。对潜在并发症的认识和及时处理对从业者至关重要。预防措施、精确技术和全面的解剖学知识可以降低风险，确保更好的患者预后。
证据级别IV：本刊要求作者为每篇文章指定证据级别。有关这些循证医学评级的完整描述，请参阅目录或在线作者指南www.springer.com/00266。
