乙型肝炎病毒携带者自发乙型肝炎表面抗原血清学清除后乙型肝炎病毒血症的流行情况和危险因素。
Prevalence of and risk factors for hepatitis B viremia after spontaneous hepatitis B surface antigen seroclearance in hepatitis B carriers.
机构信息
Liver Research Unit, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan.
出版信息
Clin Infect Dis. 2012 Jan 1;54(1):88-90. doi: 10.1093/cid/cir755. Epub 2011 Nov 3.
PMID:22052888
Abstract
In 118 previous hepatitis B surface antigen (HBsAg) carriers, low-level hepatitis B (HBV) viremia persisted at a rate of 15%-20% for >10 years after HBsAg seroclearance. The frequency of HBV viremia was significantly (P = .002) lower in patients with anti-HBsAg seroconversion (6 of 69 [8.7%]) than in those without seroconversion (15 of 49 [30.6%]).
摘要
在 118 名既往乙肝表面抗原（HBsAg）携带者中，HBsAg 血清学清除后 >10 年，低水平乙型肝炎病毒（HBV）血症的持续率为 15%-20%。HBsAg 血清转换患者（69 例中有 6 例 [8.7%]）的 HBV 血症发生率显著（P=.002）低于未发生血清转换患者（49 例中有 15 例 [30.6%]）。
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