Gottwald L, Dukowicz A, Misiewicz B, Pasz-Walczak G, Cialkowska-Rysz A
Palliative Care Unit, Chair of Oncology, Medical University of Lodz, Lodz, Poland.
Eur J Gynaecol Oncol. 2011;32(5):547-50.
In endometrial carcinoma patients, metastases to bones are rare and isolated metastases to extremities are extremely rare. We describe the case of a 59-year-old patient who underwent surgery followed by adjuvant radiotherapy due to endometrioid endometrial adenocarcinoma (grade 2, FIGO Stage II). After intervals of nine and 18 months respectively, she was diagnosed with metastatic tumours located in the right tibia and in the left humerus. The metastases were confirmed by biopsy. Following irradiation of metastatic lesions, the relief of symptoms was observed, and the patient remains under observation. We conclude that patients presenting a history of endometrial carcinoma with chronic pain in the extremities should be carefully evaluated, because although extremely rare, the carcinoma can metastasize to bones. Treatment of bone metastasis from endometrioid endometrial carcinoma by irradiation may increase quality of life and prolong survival.
在子宫内膜癌患者中，骨转移罕见，而孤立性肢体转移极为罕见。我们报告一例59岁患者，因子宫内膜样腺癌（2级，国际妇产科联盟II期）接受手术及辅助放疗。分别间隔9个月和18个月后，她被诊断为右胫骨和左肱骨出现转移性肿瘤。活检证实为转移瘤。对转移病灶进行放疗后，症状得到缓解，患者仍在接受观察。我们得出结论，有子宫内膜癌病史且四肢慢性疼痛的患者应仔细评估，因为尽管极为罕见，但该癌症可转移至骨骼。对子宫内膜样腺癌骨转移进行放疗可提高生活质量并延长生存期。
