Kim Se-Kwon, Karagozlu Mustafa Zafer
Department of Chemistry, Pukyong National University, Busan, Republic of Korea.
Adv Food Nutr Res. 2011;64:225-33. doi: 10.1016/B978-0-12-387669-0.00017-X.
Among marine organisms, marine algae are rich sources of structurally diverse bioactive compounds with various biological activities. In order to survive in a highly competitive environment, freshwater or marine algae have to develop defense strategies that result in a tremendous diversity of compounds from different metabolic pathways. Recently, their importance as a source of novel bioactive substances is growing rapidly and many reports have been published about isolated compounds from algae with biological activities. Many researchers reported anticancer activity of the compounds isolated from marine algae. Gastrointestinal tract cancer is one of the most frequent death causes of cancer in men and women. Especially stomach cancer and colon cancer are the second and third common cancer type in the world after lung cancer. Hence investigation of bioactive compounds against gastrointestinal cancer cells has recently become an important field for researchers.
在海洋生物中，海藻是结构多样且具有多种生物活性的生物活性化合物的丰富来源。为了在竞争激烈的环境中生存，淡水或海藻必须制定防御策略，这导致了来自不同代谢途径的化合物种类繁多。最近，它们作为新型生物活性物质来源的重要性迅速增加，并且已经发表了许多关于从具有生物活性的藻类中分离出的化合物的报告。许多研究人员报道了从海藻中分离出的化合物的抗癌活性。胃肠道癌是男性和女性中最常见的癌症死亡原因之一。特别是胃癌和结肠癌是继肺癌之后世界上第二和第三常见的癌症类型。因此，针对胃肠道癌细胞的生物活性化合物的研究最近已成为研究人员的一个重要领域。
