Khan R M, Khan T Z, Haq G, Zafruddin M
Department of Anaesthesiology, J.N. Medical College, Aligarh Muslim University.
Indian J Med Res. 1990 Jun;92:189-91.
The quality of extubation and circulatory changes during extubation of the trachea with or without prior xylocaine (1 mg/kg iv) were observed in 30 patients having CAD or 2 or more cardiac risk factors. 73.33 per cent of the patients receiving xylocaine had smooth extubation (grade I) in contrast to only 46.66 per cent in the control group. Also, in patients in the xylocaine group, the circulatory changes were statistically insignificant as compared to highly significant rise in rate pressure product in the control group.