State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Invest Ophthalmol Vis Sci. 2011 Dec 20;52(13):9555-60. doi: 10.1167/iovs.11-8076.
To study posterior choroidal thickness and its profile based on location in a healthy Chinese population and to determine its correlation with age and refractive error.
A total of 210 healthy volunteers (420 eyes) with no ophthalmic disease history were recruited. Choroidal scans were obtained for all eyes using enhanced depth imaging spectral-domain optical coherence tomography. Subfoveal choroidal thickness (SFCT) and choroidal thickness at 1 mm/3 mm temporal, nasal, superior, and inferior to the fovea were measured.
The choroid was thickest underneath the fovea (261.93 ± 88.42 μm). At 1 mm and 3 mm to the fovea, the choroid temporally was thicker than nasally. Mean SFCT in subjects younger than 60 years of age were 294.63 ± 75.90 μm, and no correlation between SFCT and age was noted. Mean SFCT in subjects older than 60 years of age was 196.52 ± 74.42 μm, much thinner than that for subjects younger than 60 years of age. A significant negative correlation was found between SFCT and age in subjects older than 60 years of age.
Age is critical for evaluation of choroidal thickness. However, SFCT has no correlation with age in subjects younger than 60 years of age. In subjects older than 60 years of age, SFCT was significantly negatively correlated with age, and decreased by 5.40 μm for each year of life.
研究健康中国人眼脉络膜厚度及其位置分布特征，并探讨其与年龄和屈光不正的相关性。
共招募 210 名无眼部疾病史的健康志愿者（420 只眼）。应用增强深度成像谱域光学相干断层扫描对所有眼进行脉络膜扫描。测量黄斑中心凹下脉络膜厚度（SFCT）以及距黄斑中心凹颞侧、鼻侧、上侧和下侧 1mm 和 3mm 处的脉络膜厚度。
脉络膜在黄斑中心凹下最厚（261.93±88.42μm）。在距黄斑中心凹 1mm 和 3mm 处，颞侧脉络膜厚度均大于鼻侧。60 岁以下受试者的 SFCT 平均值为 294.63±75.90μm，且 SFCT 与年龄无相关性。60 岁以上受试者的 SFCT 平均值为 196.52±74.42μm，明显小于 60 岁以下受试者。60 岁以上受试者的 SFCT 与年龄呈显著负相关。
年龄是评估脉络膜厚度的关键因素。然而，60 岁以下受试者的 SFCT 与年龄无相关性。60 岁以上受试者的 SFCT 与年龄呈显著负相关，每增加 1 岁，SFCT 减少 5.40μm。
